TXN and FST

Number of citations of the paper that reports this interaction (PubMedID 12099690)
2

Data Source:
BioGRID (two hybrid)

		TXN	FST
Description		thioredoxin	follistatin
Image
GO Annotations	Cellular Component	Cell Nucleoplasm Cytosol Extracellular Exosome	Extracellular Region Extracellular Space Nucleus Cytoplasm
	Molecular Function	RNA Binding Thioredoxin-disulfide Reductase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Peptide Disulfide Oxidoreductase Activity	Protein Binding Activin Receptor Antagonist Activity Heparan Sulfate Proteoglycan Binding Activin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Glycerol Ether Metabolic Process Response To Radiation Activation Of Protein Kinase B Activity Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of DNA Binding Cell Redox Homeostasis Negative Regulation Of Protein Export From Nucleus Positive Regulation Of Protein Kinase B Signaling Oxidation-reduction Process Cellular Oxidant Detoxification Negative Regulation Of Hydrogen Peroxide-induced Cell Death	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Hematopoietic Progenitor Cell Differentiation Multicellular Organism Development Gamete Generation Pattern Specification Process Female Gonad Development Cell Differentiation BMP Signaling Pathway Regulation Of BMP Signaling Pathway Hair Follicle Morphogenesis Negative Regulation Of Activin Receptor Signaling Pathway Odontogenesis Of Dentin-containing Tooth Keratinocyte Proliferation Negative Regulation Of Cell Differentiation Positive Regulation Of Hair Follicle Development
Pathways		Oxidative Stress Induced Senescence Detoxification of Reactive Oxygen Species Interconversion of nucleotide di- and triphosphates TP53 Regulates Metabolic Genes Protein repair The NLRP3 inflammasome The NLRP3 inflammasome Regulation of FOXO transcriptional activity by acetylation Purinergic signaling in leishmaniasis infection Purinergic signaling in leishmaniasis infection	Antagonism of Activin by Follistatin
Drugs		Phenethyl Isothiocyanate	D-Myo-Inositol-Hexasulphate
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695)	Acne (severe) ( 24927181 30542056) Alzheimer's disease (late onset) ( 30820047) Estimated glomerular filtration rate ( 31152163) Height ( 31562340) High-grade serous ovarian cancer ( 31469419) Intraocular pressure ( 29617998 29235454) Midgestational circulating levels of PCBs ( 28235828) Optic disc size ( 31809533)
Interacting Genes		25 interacting genes: ACTN4 APEX1 CDKN1A COL1A1 COPS5 DNAJA1 DYNLT1 EGFR FST GFER GPRASP2 MAP3K5 MLH1 MYD88 NCF4 NFE2 NFKB1 NR3C1 PTEN SIAH1 SRPK2 TP53 TXNIP UCHL5 VIM	9 interacting genes: BMP5 C8orf33 FN1 INHA INHBA INHBE MEST TK1 TXN
Entrez ID		7295	10468
HPRD ID		01761	00641
Ensembl ID		ENSG00000136810	ENSG00000134363
Uniprot IDs		H9ZYJ2 P10599	A0A024QZU6 P19883
PDB IDs		1AIU 1AUC 1CQG 1CQH 1ERT 1ERU 1ERV 1ERW 1M7T 1MDI 1MDJ 1MDK 1TRS 1TRU 1TRV 1TRW 1W1C 1W1E 2HSH 2HXK 2IFQ 2IIY 3E3E 3KD0 3M9J 3M9K 3QFA 3QFB 3TRX 4LL1 4LL4 4OO4 4OO5 4POK 4POL 4POM 4PUF 4TRX 5DQY	2B0U 2P6A 3HH2 5JHW
Enriched GO Terms of Interacting Partners?
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