HIRA and PAX7

Number of citations of the paper that reports this interaction (PubMedID 9731536)
35

Data Source:
HPRD (two hybrid, in vitro)

		HIRA	PAX7
Description		histone cell cycle regulator	paired box 7
Image			No pdb structure
GO Annotations	Cellular Component	HIR Complex Chromosome, Centromeric Region Nuclear Chromatin Nucleus Nucleoplasm PML Body Protein-containing Complex Extracellular Exosome	Nuclear Chromatin
	Molecular Function	DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Mitotic Sister Chromatid Segregation Osteoblast Differentiation DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Gastrulation Anatomical Structure Morphogenesis Chromatin Silencing At Centromere Regulation Of Chromatin Silencing Muscle Cell Differentiation	Chromatin Remodeling Anatomical Structure Morphogenesis Regulation Of Cell Fate Commitment Skeletal Muscle Satellite Cell Commitment Spinal Cord Association Neuron Differentiation Dorsal/ventral Neural Tube Patterning Positive Regulation Of Histone Methylation Negative Regulation Of Apoptotic Process Skeletal Muscle Tissue Regeneration Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment Embryonic Skeletal System Development Regulation Of DNA Binding Cartilage Development Muscle Tissue Morphogenesis Positive Regulation Of Myoblast Proliferation
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases			Alveolar rhabdomyosarcoma
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872)	Body mass index ( 23669352) Cleft lip with or without cleft palate ( 28054174) Knee osteoarthritis ( 28916551) Nonsyndromic cleft lip with cleft palate ( 28232668) Orofacial clefts ( 22863734 28054174) Percentage gas trapping ( 26030696) Response to amphetamines ( 22952603) Urate levels in lean individuals ( 25811787)
Interacting Genes		14 interacting genes: ASF1A CCNA2 CDK2 H2BC12 H2BC21 H2BC5 H3-3B HIRIP3 HNRNPD NFU1 OGT PAX7 UBE2I UPF1	4 interacting genes: CSNK2A1 HIRA NEDD4 SLC30A7
Entrez ID		7290	5081
HPRD ID		02583	01331
Ensembl ID		ENSG00000100084	ENSG00000009709
Uniprot IDs		P54198	P23759
PDB IDs		2I32 5YJE
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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