C6 and SART3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		C6	SART3
Description		complement C6	spliceosome associated factor 3, U4/U6 recycling protein
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GO Annotations	Cellular Component	Extracellular Region Membrane Attack Complex Extracellular Exosome	Nucleus Nucleoplasm U6atac SnRNP Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex ASAP Complex U4/U6 SnRNP U4atac/U6atac SnRNP
	Molecular Function	Protein Binding	RNA Binding Protein Binding U6 SnRNA Binding U4 SnRNA Binding U6atac SnRNA Binding Histone Binding Ubiquitin-specific Protease Binding
	Biological Process	In Utero Embryonic Development Positive Regulation Of Activation Of Membrane Attack Complex Complement Activation Complement Activation, Classical Pathway Cytolysis Regulation Of Complement Activation Innate Immune Response Positive Regulation Of Angiogenesis	Spliceosomal Tri-snRNP Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Cell Morphogenesis Nucleosome Assembly RNA Splicing Regulation Of Gene Expression Homeostasis Of Number Of Cells Hematopoietic Stem Cell Proliferation Positive Regulation Of Histone Deubiquitination
Pathways		Terminal pathway of complement Regulation of Complement cascade
Drugs
Diseases		Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency	Disseminated superficial actinic porokeratosis (DSAP)
GWAS		Blood protein levels ( 28240269) Response to fenofibrate (adiponectin levels) ( 23149075)	Acne (severe) ( 24927181)
Interacting Genes		4 interacting genes: C5 F2 OGA SART3	10 interacting genes: AR C6 COIL H2AC20 H2BC21 KPNA2 LSM7 MEGF10 PRPF3 RNPS1
Entrez ID		729	9733
HPRD ID		01956	11532
Ensembl ID		ENSG00000039537	ENSG00000075856
Uniprot IDs		P13671	A0A499FI31 Q15020
PDB IDs		3T5O 4A5W 4E0S 6H03 6H04	2DO4 5CTQ 5CTR 5CTT 5JJW 5JJX 5JPZ
Enriched GO Terms of Interacting Partners?
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