TRIO and BLMH

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRIO	BLMH
Description		trio Rho guanine nucleotide exchange factor	bleomycin hydrolase
Image
GO Annotations	Cellular Component	Cytosol Cell Projection	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding	Aminopeptidase Activity Carboxypeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity Identical Protein Binding
	Biological Process	Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway G Protein-coupled Receptor Signaling Pathway Axon Guidance Central Nervous System Development Positive Regulation Of Apoptotic Process Negative Regulation Of Fat Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction	Protein Polyubiquitination Proteolysis Response To Toxic Substance Response To Drug Homocysteine Catabolic Process
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (q) signalling events G alpha (12/13) signalling events DCC mediated attractive signaling DCC mediated attractive signaling	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel) ( 24025145) Antidepressant treatment resistance (number of drugs prescribed) ( 30700811) Asthma (childhood onset) ( 31036433) Electroencephalogram traits ( 25387704) High density lipoprotein cholesterol levels ( 30498476) Intake of total sugars ( 31005972) Major depressive disorder ( 27777418) Paclitaxel-induced neuropathy ( 23776197) Waist circumference ( 28552196)
Interacting Genes		11 interacting genes: BLMH CDC5L DISC1 EXOC1 FLNA ITSN2 MAPRE1 PTK2 PTPRF RAC1 RHOA	14 interacting genes: AP1M2 APP CYP2C8 ECSIT KBTBD7 MAST1 NTAQ1 NUDT12 PDPK1 RNF32 RPL11 RPL29 TRIO UBE2I
Entrez ID		7204	642
HPRD ID		03537	03870
Ensembl ID		ENSG00000038382	ENSG00000108578
Uniprot IDs		O75962	Q13867
PDB IDs		1NTY 2NZ8 6D8Z	1CB5 2CB5
Enriched GO Terms of Interacting Partners?
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