TRAF6 and IRAK4

  • Number of citations of the paper that reports this interaction (PubMedID 11960013)
  • 151
  • Data Source:
  • HPRD (in vitro, in vivo)

TRAF6

IRAK4

Description TNF receptor associated factor 6 interleukin 1 receptor associated kinase 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Immune reponse to smallpox (secreted TNF-alpha) ( 22610502)
  • Inflammatory bowel disease ( 27569725)
Interacting Genes 163 interacting genes: ABL1 APP ATM ATP6V1E1 ATXN3 BCL3 BEX3 BMPR1B CALCOCO2 CASP8 CAV1 CBL CD40 CUL5 CYLD DLG4 DNA2 ECSIT EDA2R EDARADD FHL2 FYN GART GSK3B GTF2I H2AX H2BC21 HNRNPA1 HSD17B10 HSPA4 IL17RB IPMK IRAK1 IRAK2 IRAK3 IRAK4 IRF5 IRF7 IRF8 JAK2 KCNQ1 LIMD1 MALT1 MAP2K1 MAP2K6 MAP2K7 MAP3K11 MAP3K14 MAP3K3 MAP3K5 MAP3K7 MAP3K8 MAPK14 MAPK8 MAPT MAST2 MATR3 MAVS MBP MCL1 MEOX2 MTOR NGFR NTRK1 NTRK2 NUMBL OTUB1 OTUB2 OTUD7B PELI3 PFN1 PINK1 PLEKHF2 PLEKHO1 POLI PPP4C PRKCZ PSMB5 PSMC1 PSMC2 PSMC3 PSMD1 PSMD12 PSMD13 PSMD6 PSMD7 PTPN6 RIPK2 RNF114 RNF31 RPL3 RPS2 RPS20 RPS27A SIGIRR SPHK1 SPOP SQSTM1 SRC STAMBP STK26 STRADB STUB1 SYK TAB1 TAB2 TAB3 TANK TAX1BP1 TDP2 TGFBR1 TICAM1 TICAM2 TIFA TIRAP TLR3 TMEM189-UBE2V1 TNFAIP3 TNFRSF11A TNFRSF13B TNFRSF19 TNFSF11 TRAF1 TRAF2 TRAF3IP1 TRAF3IP2 TRAF4 TRAF5 TRAF7 TRAFD1 TRAM1 TRIM17 TRIM25 TRIM37 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2I UBE2L3 UBE2N UBE2V1 UBOX5 UEVLD USP1 USP15 USP2 USP21 USP39 USP5 USP7 VPS52 XIAP YBX1 YES1 YWHAQ ZFAND5 ZMYND11 ZNF675 ZRANB1 19 interacting genes: ARNT EIF4EBP1 H1-1 H1-2 H1-3 H1-4 H1-5 H1-6 IKBKG IRAK1 MBP MYD88 PELI1 PELI2 PELI3 TBPL1 TICAM2 TIRAP TRAF6
Entrez ID 7189 51135
HPRD ID 03833 06051
Ensembl ID ENSG00000175104 ENSG00000198001
Uniprot IDs Q9Y4K3 B2RAP9 B4E359 Q69FE3 Q9NWZ3
PDB IDs 1LB4 1LB5 1LB6 2ECI 2JMD 3HCS 3HCT 3HCU 4Z8M 5ZUJ 6A33 2NRU 2NRY 2O8Y 2OIB 2OIC 2OID 3MOP 4RMZ 4U97 4U9A 4XS2 4Y73 4YO6 4YP8 4ZTL 4ZTM 4ZTN 5K72 5K75 5K76 5K7G 5K7I 5KX7 5KX8 5T1S 5T1T 5UIQ 5UIR 5UIS 5UIT 5UIU 5W84 5W85 6EG9 6EGA 6EGD 6EGE 6EGF 6F3D 6F3E 6F3G 6F3I 6MOM 6N8G 6O8U 6O94 6O95 6O9D 6RFI 6RFJ 6UYA
Enriched GO Terms of Interacting Partners?
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