TPD52 and SOCS2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		TPD52	SOCS2
Description		tumor protein D52	suppressor of cytokine signaling 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol Phosphatidylinositol 3-kinase Complex
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity	SH3/SH2 Adaptor Activity Growth Hormone Receptor Binding Insulin-like Growth Factor Receptor Binding Protein Binding JAK Pathway Signal Transduction Adaptor Activity 1-phosphatidylinositol-3-kinase Regulator Activity
	Biological Process	Anatomical Structure Morphogenesis B Cell Differentiation Secretion	Regulation Of Cell Growth JAK-STAT Cascade Lactation Regulation Of Signal Transduction Positive Regulation Of Signal Transduction Protein Ubiquitination Response To Estradiol Cellular Response To Hormone Stimulus Intracellular Signal Transduction Interleukin-7-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Negative Regulation Of Apoptotic Process Regulation Of Phosphatidylinositol 3-kinase Activity Post-translational Protein Modification Positive Regulation Of Neuron Differentiation Negative Regulation Of JAK-STAT Cascade Phosphatidylinositol Phosphorylation Growth Hormone Receptor Signaling Pathway Mammary Gland Alveolus Development
Pathways		Golgi Associated Vesicle Biogenesis	Interleukin-7 signaling Neddylation Growth hormone receptor signaling
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31361310 27182965 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Lapatinib-induced hepatotoxicity ( 25987243) Metabolite levels (HVA/MHPG ratio) ( 23319000) Metabolite levels (Pyroglutamine) ( 23934736) Rheumatoid arthritis ( 30423114 24390342) Self-reported allergy ( 23817569)	Height ( 28552196 20881960 25282103 25429064 23563607 31562340 18391951 18391952) Hepatic lipid content in extreme obesity ( 25246029) Joint damage in rheumatoid arthritis ( 31596875) Pubertal anthropometrics ( 23449627) Type 2 diabetes ( 30054458)
Interacting Genes		10 interacting genes: ANXA6 AR MAL2 SENP2 SOCS2 SRPK2 STUB1 TPD52L1 TPD52L2 TPD52L3	13 interacting genes: ARFIP2 BMI1 EPOR GHR IGF1R INSR PLA2G1B PRLR PTK2 RYBP SOCS3 TBK1 TPD52
Entrez ID		7163	8835
HPRD ID		04963	05490
Ensembl ID		ENSG00000076554	ENSG00000120833
Uniprot IDs		P55327	A0A024RBD2 O14508
PDB IDs			2C9W 4JGH 5BO4 6I4X 6I5J 6I5N
Enriched GO Terms of Interacting Partners?
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