TIE1 and ANGPT4

Number of citations of the paper that reports this interaction (PubMedID 10051567)
79

Data Source:
BioGRID (pull down)

		TIE1	ANGPT4
Description		tyrosine kinase with immunoglobulin like and EGF like domains 1	angiopoietin 4
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Receptor Complex	Extracellular Region Extracellular Space
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding	Transmembrane Receptor Protein Tyrosine Kinase Activator Activity Receptor Tyrosine Kinase Binding
	Biological Process	Angiogenesis Vasculogenesis In Utero Embryonic Development Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Mesoderm Development Negative Regulation Of Angiogenesis Peptidyl-tyrosine Phosphorylation Negative Regulation Of Cell Migration Response To Retinoic Acid Positive Regulation Of Kinase Activity Plasma Membrane Fusion Positive Regulation Of Angiogenesis	Angiogenesis Endothelial Cell Proliferation Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Notch Signaling Pathway Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Apoptotic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Angiogenesis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Leukocyte Migration Cellular Response To Hypoxia
Pathways			Tie2 Signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)	Food allergy ( 29030101) Intracranial aneurysm ( 29531279) Logical memory (immediate recall) in Alzheimer's disease dementia ( 29274321) Peanut allergy ( 29030101)
Interacting Genes		10 interacting genes: ANGPT1 ANGPT4 KRT40 MDFI MTMR14 PIK3R1 PSG5 PTPN11 RBPMS TEK	3 interacting genes: RHOU TEK TIE1
Entrez ID		7075	51378
HPRD ID		02572	04747
Ensembl ID		ENSG00000066056	ENSG00000101280
Uniprot IDs		B4DTW8 P35590	Q9Y264
PDB IDs		5N06
Enriched GO Terms of Interacting Partners?
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