TH and TYSND1

Number of citations of the paper that reports this interaction (PubMedID 22002062)
16

Data Source:
BioGRID (enzymatic study)

		TH	TYSND1
Description		tyrosine hydroxylase	trypsin domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Cytoplasm Mitochondrion Smooth Endoplasmic Reticulum Cytosol Synaptic Vesicle Cytoplasmic Side Of Plasma Membrane Axon Dendrite Cytoplasmic Vesicle Melanosome Membrane Neuron Projection Terminal Bouton Perikaryon	Peroxisome Peroxisomal Matrix Cytosol Membrane
	Molecular Function	Tyrosine 3-monooxygenase Activity Protein Binding Ferrous Iron Binding Ferric Iron Binding Amino Acid Binding Oxygen Binding Enzyme Binding Protein Domain Specific Binding Tetrahydrobiopterin Binding Dopamine Binding	Protease Binding Serine-type Endopeptidase Activity
	Biological Process	Response To Hypoxia Synaptic Transmission, Dopaminergic Response To Amphetamine Heart Morphogenesis Dopamine Biosynthetic Process From Tyrosine Fatty Acid Metabolic Process Sphingolipid Metabolic Process Heart Development Visual Perception Sensory Perception Of Sound Learning Memory Mating Behavior Locomotory Behavior Regulation Of Heart Contraction Response To Water Deprivation Response To Light Stimulus Response To Herbicide Response To Salt Stress Anatomical Structure Morphogenesis Animal Organ Morphogenesis Response To Zinc Ion Multicellular Organism Aging Response To Activity Aminergic Neurotransmitter Loading Into Synaptic Vesicle Glycoside Metabolic Process Phthalate Metabolic Process Cerebral Cortex Development Response To Nutrient Levels Response To Estradiol Response To Lipopolysaccharide Isoquinoline Alkaloid Metabolic Process Social Behavior Response To Isolation Stress Response To Immobilization Stress Neurotransmitter Biosynthetic Process Terpene Metabolic Process Dopamine Biosynthetic Process Epinephrine Biosynthetic Process Norepinephrine Biosynthetic Process Catecholamine Biosynthetic Process Eye Photoreceptor Cell Development Circadian Sleep/wake Cycle Eating Behavior Response To Peptide Hormone Pigmentation Response To Ethanol Response To Ether Response To Pyrethroid Embryonic Camera-type Eye Morphogenesis Response To Corticosterone Response To Electrical Stimulus Phytoalexin Metabolic Process Oxidation-reduction Process Cellular Response To Manganese Ion Cellular Response To Alkaloid Cellular Response To Nicotine Cellular Response To Glucose Stimulus Cellular Response To Growth Factor Stimulus	Proteolysis Protein Targeting To Peroxisome Protein Processing Regulation Of Fatty Acid Beta-oxidation
Pathways		Catecholamine biosynthesis	Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins TYSND1 cleaves peroxisomal proteins
Drugs		L-Phenylalanine L-Tyrosine Sapropterin Metyrosine 3-Tyrosine
Diseases		Primary torsion dystonia (PTD)
GWAS		Celiac disease ( 23936387) Height ( 31562340) Prostate cancer ( 19767753) Prostate cancer (early onset) ( 24740154) Prostate cancer (SNP x SNP interaction) ( 22219177) Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926) Type 1 diabetes in high risk HLA genotype individuals (time to event) ( 29310926) Type 2 diabetes ( 31324766 25102180)
Interacting Genes		12 interacting genes: CAMK2G CDK11B CSNK2A1 MAPK1 MAPK3 MAPKAPK2 PRKACA RPS6KA5 SNCA TYSND1 YWHAB YWHAZ	3 interacting genes: ACOX1 OIT3 TH
Entrez ID		7054	219743
HPRD ID		01865	15593
Ensembl ID		ENSG00000180176	ENSG00000156521
Uniprot IDs		P07101 P78428	Q2T9J0
PDB IDs		2XSN 4J6S
Enriched GO Terms of Interacting Partners?
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