LEFTY2 and ACSS3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		LEFTY2	ACSS3
Description		left-right determination factor 2	acyl-CoA synthetase short chain family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Collagen-containing Extracellular Matrix	Mitochondrial Matrix
	Molecular Function	Cytokine Activity Transforming Growth Factor Beta Receptor Binding Growth Factor Activity	Acetate-CoA Ligase Activity ATP Binding Butyrate-CoA Ligase Activity Propionate-CoA Ligase Activity
	Biological Process	Platelet Degranulation Transforming Growth Factor Beta Receptor Signaling Pathway Multicellular Organism Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation BMP Signaling Pathway SMAD Protein Signal Transduction	Ketone Body Biosynthetic Process
Pathways		Platelet degranulation Signaling by NODAL Regulation of signaling by NODAL	Synthesis of Ketone Bodies
Drugs
Diseases
GWAS			Age-related cataracts (age at onset) ( 25352737) Alcohol consumption ( 31358974) Bitter alcoholic beverage consumption ( 31046077) Lateral orbital frontal cortex volume ( 31530798) Medial orbital frontal cortex volume ( 31530798) Pars orbitalis volume ( 31530798) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457) Prudent dietary pattern ( 28644415) Response to antidepressant treatment (citalopram) ( 23726668)
Interacting Genes		2 interacting genes: ACSS3 MAPK8IP2	1 interacting genes: LEFTY2
Entrez ID		7044	79611
HPRD ID		03526	13385
Ensembl ID		ENSG00000143768	ENSG00000111058
Uniprot IDs		A1NY82 O00292	A0A0B4J1R2 Q9H6R3
PDB IDs
Enriched GO Terms of Interacting Partners?
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