TGFB1I1 and PLA2G3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		TGFB1I1	PLA2G3
Description		transforming growth factor beta 1 induced transcript 1	phospholipase A2 group III
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Nuclear Matrix Collagen-containing Extracellular Matrix	Extracellular Region Extracellular Space Centriole Plasma Membrane Mast Cell Granule
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Metal Ion Binding Roundabout Binding Androgen Receptor Binding I-SMAD Binding	Metal Ion Binding Calcium-dependent Phospholipase A2 Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
	Biological Process	Transcription By RNA Polymerase II Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Response To Heat Positive Regulation Of Epithelial To Mesenchymal Transition Wnt Signaling Pathway Morphogenesis Of Embryonic Epithelium Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Androgen Receptor Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Epithelial Cell Differentiation Substrate Adhesion-dependent Cell Spreading Endothelial Cell Migration Cell Fate Commitment Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated	Acrosome Assembly Phospholipid Metabolic Process Sperm Axoneme Assembly Lipid Catabolic Process Lipoxygenase Pathway Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Mast Cell Degranulation Arachidonic Acid Secretion Cilium Assembly
Pathways			Acyl chain remodelling of PC Acyl chain remodelling of PE Acyl chain remodelling of PG
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Gut microbiota (beta diversity) ( 27723756) Paclitaxel-induced neuropathy ( 23776197)
Interacting Genes		29 interacting genes: AR CBLB CBLC CDKN2B CRKL CSK EP300 FKBP1A GIT1 GIT2 GP1BB HIPK3 HSPB1 ITGA4 MAPK15 NEDD4L NR3C1 PLA2G3 PTK2 PTK2B PTPN12 SDC4 SLC6A3 SMAD7 SVIL TGFBR2 TRAF4 UBQLN4 VCL	2 interacting genes: PVR TGFB1I1
Entrez ID		7041	50487
HPRD ID		03831	07144
Ensembl ID		ENSG00000140682	ENSG00000100078
Uniprot IDs		A0A024QZE7 O43294	Q9NZ20
PDB IDs
Enriched GO Terms of Interacting Partners?
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