TMBIM6 and VTI1A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		TMBIM6	VTI1A
Description		transmembrane BAX inhibitor motif containing 6	vesicle transport through interaction with t-SNAREs 1A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Mitochondrial Membrane	Golgi Membrane Endosome Autophagosome Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Clathrin-coated Vesicle SNARE Complex Late Endosome Membrane Trans-Golgi Network Membrane Neuronal Cell Body Intracellular Membrane-bounded Organelle Neuron Projection Terminus Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding Endoribonuclease Inhibitor Activity	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Autophagy Negative Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Protein Binding Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of RNA Splicing Cellular Response To Unfolded Protein Negative Regulation Of Apoptotic Process Negative Regulation Of Immunoglobulin Secretion Negative Regulation Of Endoribonuclease Activity Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Response To L-glutamate Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Signaling Pathway	Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Autophagy Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Voluntary Musculoskeletal Movement Golgi Ribbon Formation
Pathways			Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		General cognitive ability ( 29844566)	Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Carotid intima media thickness ( 30510157) Cognitive decline (age-related) ( 28078323) Colorectal cancer ( 26965516 30529582 25105248) Colorectal cancer or advanced adenoma ( 30510241) Heel bone mineral density ( 30598549) Lung cancer ( 23143601) Multiple sclerosis ( 23412934) Non-glioblastoma glioma ( 28346443 26424050) Non-small cell lung cancer ( 31326317) QRS duration ( 30679814 27577874 31251759 27659466)
Interacting Genes		5 interacting genes: BCL2 BCL2L1 CERS2 GLP1R VTI1A	2 interacting genes: STX16 TMBIM6
Entrez ID		7009	143187
HPRD ID		02851	18290
Ensembl ID		ENSG00000139644	ENSG00000151532
Uniprot IDs		A0A024R0Z5 P55061	Q96AJ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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