TRB and CTCF

Number of citations of the paper that reports this interaction (PubMedID 20404925)
11

Data Source:
BioGRID (pull down, pull down)

		TRB	CTCF
Description		T cell receptor beta locus	CCCTC-binding factor
Image		No pdb structure
GO Annotations	Cellular Component		Chromosome, Centromeric Region Condensed Chromosome Nucleus Nucleoplasm Nucleolus
	Molecular Function		RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Chromatin Insulator Sequence Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Chromosome Segregation Negative Regulation Of Cell Proliferation Maintenance Of DNA Methylation Positive Regulation Of Gene Expression Nucleosome Positioning Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Gene Expression, Epigenetic Regulation Of Molecular Function, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Centromeric Sister Chromatid Cohesion Protein Localization To Chromosome, Centromeric Region
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Narcolepsy ( 24204295)	Elevated fasting plasma glucose ( 30004843) HDL cholesterol ( 19060911)
Interacting Genes		14 interacting genes: CD1D CD247 CD3D CD3E CD3G CTCF HLA-A HLA-B HLA-DRB1 NCOA6 TAF1B TRA TRAT1 TRD	19 interacting genes: CHD1L CHD7 CHD8 HMGB1 MT-ND4 PARP1 POLR2A RAD51 RALA RHOU RXRA SIN3A SMAD3 SMAD4 SUZ12 THRB TRB YBX1 ZMYM4
Entrez ID		6957	10664
HPRD ID		01739	05005
Ensembl ID			ENSG00000102974
Uniprot IDs			A0A2R8YFL0 P49711
PDB IDs			1X6H 2CT1 5K5H 5K5I 5K5J 5K5L 5KKQ 5T00 5T0U 5UND 5YEF 5YEG 5YEH 5YEL
Enriched GO Terms of Interacting Partners?
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