TCP1 and CCT7

Number of citations of the paper that reports this interaction (PubMedID 9250675)
45

Data Source:
HPRD (in vitro)

		TCP1	CCT7
Description		t-complex 1	chaperonin containing TCP1 subunit 7
Image
GO Annotations	Cellular Component	Pericentriolar Material Acrosomal Vesicle Zona Pellucida Receptor Complex Nuclear Heterochromatin Golgi Apparatus Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Exosome	Cytoplasm Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Unfolded Protein Binding	Protein Binding ATP Binding Identical Protein Binding Unfolded Protein Binding
	Biological Process	Protein Folding Tubulin Complex Assembly Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Interleukin-12-mediated Signaling Pathway Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm Protein Stabilization Positive Regulation Of Telomerase Activity ScaRNA Localization To Cajal Body Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body Regulation Of Macrophage Apoptotic Process	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS			General cognitive ability ( 29844566)
Interacting Genes		11 interacting genes: CBFA2T2 CCT5 CCT7 CDC20 FANCA PDCL SH3BP4 TUBA4A TUBA8 VRK2 YWHAQ	19 interacting genes: ANXA1 ANXA7 APP ATP5F1C CDKN1A CEBPE CRMP1 DNM2 EEF1G KAT5 KRAS MED31 NKX3-1 PRPF40A RAP1B RCC1 SUMO4 TCP1 ZNRD2
Entrez ID		6950	10574
HPRD ID		01748	06896
Ensembl ID		ENSG00000120438	ENSG00000135624
Uniprot IDs		E7EQR6 P17987	Q99832
PDB IDs		6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8	6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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