TAT and GLUL

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		TAT	GLUL
Description		tyrosine aminotransferase	glutamate-ammonia ligase
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GO Annotations	Cellular Component	Cellular_component Mitochondrion Cytosol	Nucleus Mitochondrion Rough Endoplasmic Reticulum Cytosol Plasma Membrane Protein-containing Complex Perikaryon Myelin Sheath Axon Terminus Extracellular Exosome Glial Cell Projection
	Molecular Function	L-tyrosine:2-oxoglutarate Aminotransferase Activity Protein Binding Amino Acid Binding Pyridoxal Phosphate Binding Identical Protein Binding	Magnesium Ion Binding Glutamate-ammonia Ligase Activity Protein Binding ATP Binding Glutamate Binding Protein-cysteine S-palmitoyltransferase Activity Manganese Ion Binding Identical Protein Binding Dynein Light Chain Binding
	Biological Process	2-oxoglutarate Metabolic Process Glutamate Metabolic Process L-phenylalanine Catabolic Process Tyrosine Catabolic Process Response To Oxidative Stress Biosynthetic Process Response To Mercury Ion Response To Glucocorticoid	Neurotransmitter Uptake Angiogenesis Glutamate Catabolic Process Glutamine Biosynthetic Process Cell Proliferation Cellular Amino Acid Biosynthetic Process Cellular Response To Starvation Response To Glucose Regulation Of Endothelial Cell Migration Protein Palmitoylation Ammonia Assimilation Cycle Positive Regulation Of Insulin Secretion Ribosome Biogenesis Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Sprouting Angiogenesis Regulation Of Protein Localization To Nucleolus
Pathways		Tyrosine catabolism	Astrocytic Glutamate-Glutamine Uptake And Metabolism Glutamate and glutamine metabolism
Drugs		Pyridoxal Phosphate L-Phenylalanine L-Tyrosine Glutamic Acid	L-Glutamine Glutamic Acid
Diseases		Tyrosinemia; Tyrosinemia, type I; Tyrosinemia, type II; Tyrosinemia, type III; Hawkinsinuria	Congenital systemic glutamine deficiency (CSGD); Glutamine synthetase deficiency
GWAS		Chronotype ( 30696823) Metabolite levels ( 22286219 22916037) Morning person ( 30696823) Urate levels ( 31578528)	Cardiovascular heart disease in diabetics ( 23982368) Morning person ( 30696823)
Interacting Genes		3 interacting genes: GLUL GRN UBE3A	22 interacting genes: CASP8AP2 CRBN CYP39A1 DYNLL1 EP300 HIPK1 HIPK3 HSD17B10 HTR2A MT-ND5 NFKB1 NUDT18 PIAS1 PIAS2 PIAS3 PLEKHF2 PPARD RABEPK RBBP6 SKIL TAT UBE2I
Entrez ID		6898	2752
HPRD ID		11776	00701
Ensembl ID		ENSG00000198650	ENSG00000135821
Uniprot IDs		A0A140VKB7 P17735	A8YXX4 P15104
PDB IDs		3DYD	2OJW 2QC8
Enriched GO Terms of Interacting Partners?
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