TARBP2 and ZNF346

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TARBP2	ZNF346
Description		TARBP2 subunit of RISC loading complex	zinc finger protein 346
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol RISC Complex Nuclear Body Perinuclear Region Of Cytoplasm RISC-loading Complex	Nucleus Nucleolus Cytoplasm
	Molecular Function	Double-stranded RNA Binding Protein Binding Enzyme Binding SiRNA Binding MiRNA Binding Pre-mRNA Binding Identical Protein Binding Protein Homodimerization Activity Protein N-terminus Binding Pre-miRNA Binding	RNA Binding Double-stranded RNA Binding Protein Binding Zinc Ion Binding Enzyme Binding MiRNA Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Spermatid Development Single Fertilization MiRNA Metabolic Process Production Of SiRNA Involved In RNA Interference Targeting Of MRNA For Destruction Involved In RNA Interference Pre-miRNA Processing SiRNA Loading Onto RISC Involved In RNA Interference Production Of MiRNAs Involved In Gene Silencing By MiRNA Multicellular Organism Growth MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Skeletal Muscle Tissue Regeneration Positive Regulation Of Viral Genome Replication Positive Regulation Of Translation Regulation Of Viral Transcription Negative Regulation Of Defense Response To Virus By Host Positive Regulation Of Muscle Cell Differentiation Neural Precursor Cell Proliferation Regulation Of Production Of SiRNA Involved In RNA Interference Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA	Positive Regulation Of Apoptotic Process
Pathways		MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Height ( 28552196 31562340) Type 2 diabetes ( 30718926) Uterine fibroids ( 30194396 31649266) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		22 interacting genes: AGO2 APP DICER1 EIF2AK2 HDHD2 HSPB1 IKBKG KCNIP3 MAPK8IP2 MED21 NEDD4L NEUROG1 NF2 NUDT18 PRKRA RBM14 TCEANC TGIF2 TOP1 TRAF4 VAV2 ZNF346	5 interacting genes: ANKHD1 EIF2AK2 ILF3 TARBP2 XPO5
Entrez ID		6895	23567
HPRD ID		05446	05606
Ensembl ID		ENSG00000139546	ENSG00000113761
Uniprot IDs		A0A024RB49 Q15633	B7Z4J8 B7Z4N4 Q9UL40
PDB IDs		2CPN 3ADL 3LLH 4WYQ 5N8L 5N8M 5ZAK 5ZAL 5ZAM	2MKD 2MKN
Enriched GO Terms of Interacting Partners?
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