KLF5 and ANP32B

Number of citations of the paper that reports this interaction (PubMedID 18039846)
12

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)

		KLF5	ANP32B
Description		Kruppel like factor 5	acidic nuclear phosphoprotein 32 family member B
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Golgi Apparatus Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Nucleolus Cytoplasm Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding MRF Binding Metal Ion Binding	Protein Binding Histone Binding RNA Polymerase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation Skeletal Muscle Satellite Cell Differentiation Satellite Cell Activation Involved In Skeletal Muscle Regeneration Myotube Differentiation Involved In Skeletal Muscle Regeneration Microvillus Assembly Regulation Of Microvillus Assembly Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Intestinal Epithelial Cell Development Positive Regulation Of Transcription By Transcription Factor Localization Cellular Response To Organic Cyclic Compound Cell-cell Signaling Via Exosome Cellular Response To Peptide Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor	Vasculature Development Nucleosome Assembly Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Ventricular System Development Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Positive Regulation Of Protein Export From Nucleus Inner Ear Development Roof Of Mouth Development
Pathways		Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of granulopoiesis
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29679657) Blood urea nitrogen levels ( 31152163) Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709 29058716) Breast Cancer in BRCA1 mutation carriers ( 29058716) Chronotype ( 30696823) Colorectal cancer ( 30529582) Colorectal cancer or advanced adenoma ( 30510241) Creatine kinase levels ( 29403010) Endometrial cancer ( 30093612 27008869) Endometrial cancer (endometrioid histology) ( 30093612) Intraocular pressure ( 29785010 31959993) Pancreatic cancer ( 29422604 20101243 26098869 25086665) Prostate cancer ( 31562322 26443449) Systolic blood pressure ( 30224653) Type 2 diabetes ( 25760438)	Alopecia areata ( 25608926) Coronary artery disease ( 29212778) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252) Red blood cell count ( 27863252) Serum thyroid-stimulating hormone levels ( 25436638)
Interacting Genes		27 interacting genes: ANP32B ATXN3L BAP1 CREBBP EP300 ESR1 FBXW7 GSK3B GTF2B GTF2E2 GTF2F2 HDAC1 JUN NCOR1 NCOR2 NFKB1 PARP1 PPARG PRKCA PRKCD RARA RXRA SET SMURF2 TBP UBE2I WWP1	21 interacting genes: APP CHAF1A CSNK2A1 ELAVL1 ESR1 FAM3A H2AC1 H2BC1 H3C1 H4C1 HNF4A KLF5 KPNA1 KPNA5 MEOX2 POLR1A SDCBP SMAD2 SMARCD1 UCHL5 XPO1
Entrez ID		688	10541
HPRD ID		04212	09803
Ensembl ID		ENSG00000102554	ENSG00000136938
Uniprot IDs		Q13887 Q5T6X2	Q92688
PDB IDs		2EBT	2ELL 2RR6
Enriched GO Terms of Interacting Partners?
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