TAF7 and TRIM22

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		TAF7	TRIM22
Description		TATA-box binding protein associated factor 7	tripartite motif containing 22
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex Transcription Factor TFIID Complex Golgi Apparatus Transcription Factor TFTC Complex MLL1 Complex	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cajal Body Nuclear Body Nuclear Speck
	Molecular Function	TFIIH-class Transcription Factor Complex Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Histone Acetyltransferase Binding Vitamin D Receptor Binding Transcription Regulatory Region DNA Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity H3K27me3 Modified Histone Binding P-TEFb Complex Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Transferase Activity Protein Kinase Binding Protein Binding, Bridging Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spermine Transport DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Histone Acetylation Negative Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Histone H4 Acetylation Regulation Of Signal Transduction By P53 Class Mediator	Regulation Of Transcription, DNA-templated Immune Response Response To Virus Positive Regulation Of Autophagy Viral Process Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	Interferon gamma signaling
Drugs
Diseases
GWAS		Mean platelet volume ( 27863252)	Coronary artery disease ( 29212778)
Interacting Genes		27 interacting genes: AHR CDK7 CDK9 CPSF1 FAU GATA1 H3-4 HSF1 IKBKG MAP1LC3B RBM6 SETD7 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF5 TAF6 TAF8 TAF9 TRIM22 TRIM24 YWHAE ZSCAN1	10 interacting genes: CASK CIC CREB1 LGALS3 LGALS8 MFHAS1 RERE TAF7 USP7 ZZZ3
Entrez ID		6879	10346
HPRD ID		07196	05951
Ensembl ID		ENSG00000178913	ENSG00000132274
Uniprot IDs		Q15545	B4DQS5 Q8IYM9
PDB IDs		4RGW 5FUR 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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