SUV39H1 and KLF15

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		SUV39H1	KLF15
Description		suppressor of variegation 3-9 homolog 1	Kruppel like factor 15
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Heterochromatin Condensed Nuclear Chromosome Nucleus Nuclear Lamina Nucleoplasm Chromatin Silencing Complex RDNA Heterochromatin	Nuclear Chromatin Cell Nucleus
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding S-adenosylmethionine-dependent Methyltransferase Activity Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity Histone Methyltransferase Activity (H3-K9 Specific) Protein N-terminus Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Silencing At RDNA Chromatin Organization RRNA Processing Cellular Response To DNA Damage Stimulus Cell Cycle Viral Process Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia	Cellular Glucose Homeostasis Regulation Of Transcription By RNA Polymerase II Glial Cell Differentiation Cardiac Muscle Hypertrophy In Response To Stress Response To Insulin Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Glucose Import Glomerular Visceral Epithelial Cell Differentiation Cellular Response To Peptide Negative Regulation Of Peptidyl-lysine Acetylation
Pathways		PKMTs methylate histone lysines SIRT1 negatively regulates rRNA expression	BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS			Macular telangiectasia type 2 ( 28250457) Male-pattern baldness ( 28196072) Manganese levels ( 26025379) Metabolite levels ( 23378610) Urate levels ( 31578528)
Interacting Genes		126 interacting genes: ATE1 ATF3 ATP6V1B1 BAHD1 BCL11B C4orf17 C8orf74 CBX1 CBX4 CBX5 CCDC151 CDC23 CDCA4 CDCA7L CEP70 CFAP100 CLK3 CRBN CREBBP CRELD2 DBF4B DCAF8 DDB1 DNMT1 DNMT3A DNMT3B ELOF1 EP300 ESR1 EZH2 FGD5 FOXR2 FRMD6 FUS FYN GPATCH2L GTF2H2C_2 GTPBP2 H3-3A H3-4 H3-5 H3C1 H3C15 HDAC1 HDAC2 HDAC3 HDAC5 HOOK2 HOXA1 HOXC4 ID1 ID2 IGFBP4 IL16 ING4 INTS2 KDM1A KLF15 KLHDC4 KLHL20 KRTAP10-7 LDHAL6B LENG8 LHX8 LINC02875 LNX1 LOXL4 LZTS2 MALT1 MBD1 MBD4 MCRS1 MSANTD3 MTF2 MTO1 MYOD1 NR1H2 NR1H3 OPA3 PHF19 PML PNKP PRIM2 PRMT6 PSMC1 RASSF1 RASSF2 RB1 RBBP4 RBBP7 RBL1 RBL2 RIN3 RRP8 RSPO2 RUNX1 SBF1 SLFN12 SMAD1 SMAD5 SPATA24 SPRED1 SPSB1 SRGAP3 STX11 STX19 TEX35 THRA TMEM11 TNFAIP1 TNS2 U2AF1 WDFY3 WIZ ZBTB24 ZCCHC17 ZKSCAN5 ZNF165 ZNF436 ZNF451 ZNF557 ZNF581 ZNF649 ZNF670 ZNF829 ZSCAN9	10 interacting genes: ANKS1A APPL1 CRK PIK3R3 PRKAB2 SNX13 STAT3 SUV39H1 TCF21 ZBTB24
Entrez ID		6839	28999
HPRD ID		02221	07568
Ensembl ID		ENSG00000101945	ENSG00000163884
Uniprot IDs		O43463	Q9UIH9
PDB IDs		3MTS	2ENT
Enriched GO Terms of Interacting Partners?
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