STX3 and STXBP2

Number of citations of the paper that reports this interaction (PubMedID 26186194)
367

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro, in vivo)

		STX3	STXBP2
Description		syntaxin 3	syntaxin binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Vacuole Plasma Membrane Cell-cell Junction Synaptic Vesicle Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Lamellipodium Dendrite Growth Cone SNARE Complex Melanosome Specific Granule Azurophil Granule Zymogen Granule Membrane Presynaptic Membrane Neuron Projection Presynaptic Active Zone Membrane Extracellular Exosome Schaffer Collateral - CA1 Synapse Postsynapse Glutamatergic Synapse	Extracellular Region Cytosol Plasma Membrane Apical Plasma Membrane Specific Granule Azurophil Granule Zymogen Granule Membrane Cytolytic Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Arachidonic Acid Binding	Protein Binding Syntaxin-1 Binding Syntaxin-3 Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Fusion Positive Regulation Of Cell Proliferation Synaptic Vesicle Docking Cytokine-mediated Signaling Pathway Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Positive Regulation Of Cell Adhesion Vesicle Docking Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface	Leukocyte Mediated Cytotoxicity Platelet Degranulation Vesicle Docking Involved In Exocytosis Protein Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation Cellular Response To Interferon-gamma
Pathways		Other interleukin signaling	Platelet degranulation Other interleukin signaling
Drugs
Diseases
GWAS		High chromosomal aberration frequency (chromosome type) ( 31586183)
Interacting Genes		20 interacting genes: CPLX2 DNAJC5 EVI5 LMNA NAPB SNAP23 SNAP25 SNAP29 STX4 STXBP1 STXBP2 SYT1 SYT4 SYT7 TBC1D30 TRPC3 TXLNA VAMP3 VAMP7 VAMP8	13 interacting genes: DDX20 GEMIN2 GEMIN4 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2
Entrez ID		6809	6813
HPRD ID		15985	03423
Ensembl ID		ENSG00000166900	ENSG00000076944
Uniprot IDs		Q13277 Q53YE2	Q15833 Q53GF4
PDB IDs			4CCA
Enriched GO Terms of Interacting Partners?
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