SPTB and CSRP3

Number of citations of the paper that reports this interaction (PubMedID 10751147)
30

Data Source:
HPRD (in vitro, in vivo)

		SPTB	CSRP3
Description		spectrin beta, erythrocytic	cysteine and glycine rich protein 3
Image
GO Annotations	Cellular Component	Cytosol Spectrin Spectrin-associated Cytoskeleton Actin Cytoskeleton Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Protein-containing Complex	Cell Nucleus Cytoplasm Cytoskeleton Z Disc
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Ankyrin Binding Actin Filament Binding	Actin Binding Protein Binding Structural Constituent Of Muscle Telethonin Binding Identical Protein Binding Actinin Binding Metal Ion Binding
	Biological Process	MAPK Cascade ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Axon Guidance Actin Filament Capping	Regulation Of The Force Of Heart Contraction Cardiac Muscle Hypertrophy Cellular Calcium Ion Homeostasis Inflammatory Response Skeletal Muscle Tissue Development Insulin Receptor Signaling Pathway Actin Cytoskeleton Organization T-tubule Organization Protein Localization To Organelle Detection Of Muscle Stretch Glucose Homeostasis Sarcomere Organization Positive Regulation Of Transcription By RNA Polymerase II Cardiac Muscle Tissue Development Cardiac Myofibril Assembly Cardiac Muscle Contraction Muscle Tissue Development Protein Kinase C Signaling Regulation Of Protein Localization To Plasma Membrane
Pathways		NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport
Drugs
Diseases		Hereditary elliptocytosis (HE) Hereditary spherocytosis (SPH)	Hypertrophic cardiomyopathy (HCM)
GWAS		Daytime sleep phenotypes ( 27126917) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Obesity-related traits ( 23251661) Pediatric areal bone mineral density (radius) ( 28181694) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Type 2 diabetes ( 31049640)	Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mosquito bite size ( 28199695) Red blood cell count ( 27863252)
Interacting Genes		14 interacting genes: ACTB ADD1 ANK1 AP1G1 CSRP3 DMTN EPB41 MAPT NCAM1 SH2D2A SPTA1 SPTAN1 STAT1 YWHAQ	9 interacting genes: ACTN1 HDAC4 LDHD MYF6 MYOD1 MYOG NHLH1 RIN3 SPTB
Entrez ID		6710	8048
HPRD ID		01686	07525
Ensembl ID		ENSG00000070182	ENSG00000129170
Uniprot IDs		P11277	A2TDB8 P50461
PDB IDs		1S35 3EDU 3F57 3KBT 3KBU 3LBX	2O10 2O13
Enriched GO Terms of Interacting Partners?
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