DST and SH3BP5

Number of citations of the paper that reports this interaction (PubMedID 17043677)
168

Data Source:
BioGRID (two hybrid)

		DST	SH3BP5
Description		dystonin	SH3 domain binding protein 5
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GO Annotations	Cellular Component	Basement Membrane Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Intermediate Filament Focal Adhesion Cell Cortex Basal Plasma Membrane Microtubule Cytoskeleton Membrane Integral Component Of Membrane Z Disc Hemidesmosome Cell Leading Edge Cytoplasmic Vesicle H Zone Microtubule Plus-end Axon Cytoplasm	Nucleoplasm Cytoplasm Mitochondrion Nuclear Body Cytoplasmic Vesicle Membrane
	Molecular Function	Actin Binding Integrin Binding Structural Molecule Activity Calcium Ion Binding Protein Binding Microtubule Binding Protein C-terminus Binding Microtubule Plus-end Binding	Protein Kinase Inhibitor Activity Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity SH3 Domain Binding
	Biological Process	Cytoskeleton Organization Cell Adhesion Integrin-mediated Signaling Pathway Retrograde Axonal Transport Response To Wounding Maintenance Of Cell Polarity Cytoplasmic Microtubule Organization Hemidesmosome Assembly Wound Healing Intermediate Filament Cytoskeleton Organization Cell Motility	Signal Transduction Intracellular Signal Transduction Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways		Type I hemidesmosome assembly
Drugs
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) Attention function in attention deficit hyperactive disorder ( 26174813) Cerebrospinal fluid clusterin levels ( 26545630) Daytime sleep phenotypes ( 27126917) Heel bone mineral density ( 30598549) Menarche (age at onset) ( 25231870) Small cell lung carcinoma ( 28604730)	Alcohol and nicotine co-dependence ( 22488850) Alcohol dependence ( 21956439) Heschl's gyrus morphology ( 25130324) Prudent dietary pattern ( 28644415)
Interacting Genes		27 interacting genes: APC CALM1 CDC5L CELSR3 CEP63 COL17A1 DCTN1 DISC1 DTNBP1 ECPAS ERBIN EXOC1 ITGB4 ITSN2 KIAA1549 KRT14 KRT5 MAPK6 MTNR1B NFYC PAK2 PRKAB2 PRKD2 SH3BP5 SMAD9 TNIK TRAF3IP1	14 interacting genes: APP BTK CDC5L DISC1 DST EXOC1 MAPK10 MAPK12 MAPK8 MAPK9 SOS1 SPTBN1 SYNE1 TNKS
Entrez ID		667	9467
HPRD ID		00222	12030
Ensembl ID		ENSG00000151914	ENSG00000131370
Uniprot IDs		B4DGY0 B4DSS9 E9PHM6 F6QMI7 F8W9J4 Q03001 Q6P0N6	A0A024R2J3 O60239
PDB IDs		3GJO	4H3B 6DJL 6IXE 6IXF 6IXG 6IXV
Enriched GO Terms of Interacting Partners?
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