SOX4 and RP1L1

Number of citations of the paper that reports this interaction (PubMedID 25969425)
1

Data Source:
BioGRID (two hybrid)

		SOX4	RP1L1
Description		SRY-box transcription factor 4	RP1 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Cell Nucleus Nucleoplasm Cytoplasm Mitochondrion Nuclear Transcription Factor Complex	Photoreceptor Outer Segment Microtubule Axoneme Photoreceptor Connecting Cilium
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding MiRNA Binding
	Biological Process	Skeletal System Development Neural Tube Formation Pro-B Cell Differentiation Mitral Valve Morphogenesis Cardiac Ventricle Formation Cardiac Right Ventricle Morphogenesis Atrial Septum Primum Morphogenesis Noradrenergic Neuron Differentiation Regulation Of Transcription, DNA-templated DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Heart Development Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Anatomical Structure Morphogenesis Glial Cell Proliferation Spinal Cord Development Spinal Cord Motor Neuron Differentiation Glial Cell Development Cell Differentiation T Cell Differentiation Endocrine Pancreas Development Negative Regulation Of Protein Ubiquitination Regulation Of Protein Stability Positive Regulation Of Insulin Secretion Somatic Stem Cell Population Maintenance Ascending Aorta Morphogenesis Glucose Homeostasis DNA Damage Response, Detection Of DNA Damage Positive Regulation Of Apoptotic Process Positive Regulation Of Translation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Sympathetic Nervous System Development Protein Stabilization Limb Bud Formation Ventricular Septum Morphogenesis Negative Regulation Of Cell Death Neuroepithelial Cell Differentiation Kidney Morphogenesis Cellular Response To Glucose Stimulus Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of N-terminal Peptidyl-lysine Acetylation	Visual Perception Axoneme Assembly Intracellular Signal Transduction Photoreceptor Cell Development Photoreceptor Cell Maintenance Retina Development In Camera-type Eye
Pathways		Deactivation of the beta-catenin transactivating complex
Drugs
Diseases			Occult macular dystrophy (OMD)
GWAS		Bone mineral density ( 21533022) Cardiac hypertrophy ( 21348951) Endometrial cancer ( 30093612 27008869) Endometrial cancer (endometrioid histology) ( 30093612) Metabolite levels ( 23823483) Pulmonary function (smoking interaction) ( 23284291)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Heart rate response to exercise ( 29769521) LDL cholesterol ( 30275531) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Obesity-related traits ( 23251661) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		34 interacting genes: AKT1 APOC3 AURKA CAPN15 CDKN2A CTR9 DACH1 EDF1 FOXH1 FZR1 IGF1 ITIH1 KRAS MINPP1 MNT MYC NANOGNB NF1 NF2 NSD3 PLD3 PLXNB1 RGSL1 RHOU RP1L1 SCNN1G SDCBP SMARCA4 STK11 TERT TNNI3 TSC1 UBE2I WT1	1 interacting genes: SOX4
Entrez ID		6659	94137
HPRD ID		01695	10546
Ensembl ID		ENSG00000124766	ENSG00000183638
Uniprot IDs		Q06945	Q8IWN7
PDB IDs
Enriched GO Terms of Interacting Partners?
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