SNAP25 and GOSR1

Number of citations of the paper that reports this interaction (PubMedID 9325254)
13

Data Source:
BioGRID (pull down)

		SNAP25	GOSR1
Description		synaptosome associated protein 25	golgi SNAP receptor complex member 1
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Cytoplasm Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Synaptic Vesicle Voltage-gated Potassium Channel Complex Membrane Cell Junction Growth Cone BLOC-1 Complex SNARE Complex Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Vesicle Specific Granule Membrane Somatodendritic Compartment Presynaptic Membrane Neuron Projection Perinuclear Region Of Cytoplasm Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Tertiary Granule Membrane Postsynapse Glutamatergic Synapse	Golgi Membrane Golgi Apparatus Golgi Medial Cisterna Cis-Golgi Network Cytosol Membrane Integral Component Of Membrane Transport Vesicle SNARE Complex
	Molecular Function	Voltage-gated Potassium Channel Activity SNAP Receptor Activity Protein Binding Syntaxin-1 Binding Syntaxin Binding Calcium-dependent Protein Binding	SNAP Receptor Activity
	Biological Process	Neurotransmitter Uptake Exocytosis Vesicle Fusion Chemical Synaptic Transmission Neurotransmitter Secretion Locomotory Behavior Associative Learning Regulation Of Neuron Projection Development Glutamate Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Docking Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Regulation Of Insulin Secretion Long-term Synaptic Potentiation Potassium Ion Transmembrane Transport Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Neurotransmitter Receptor Internalization	ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Vesicle Fusion Protein Transport Retrograde Transport, Endosome To Golgi Regulation Of Vesicle Targeting, To, From Or Within Golgi
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Regulation of insulin secretion Other interleukin signaling Toxicity of botulinum toxin type A (BoNT/A) Toxicity of botulinum toxin type C (BoNT/C) Toxicity of botulinum toxin type E (BoNT/E) Neutrophil degranulation GABA synthesis, release, reuptake and degradation	COPI-mediated anterograde transport Intra-Golgi traffic
Drugs		Botulinum Toxin Type A
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Psychosis proneness (hypomanic personality scale and revised social anhedonia scale) ( 28525603)
Interacting Genes		35 interacting genes: APP CENPF CPLX1 DNM1 FBXO7 GOSR1 HGS ITSN1 KCNB1 KIF5B NAPA PRKACA PRKCA PRRT2 RIMS1 SCAMP1 SNAPIN SRCIN1 STX11 STX12 STX1A STX2 STX3 STX4 STX5 STXBP6 SYT1 SYT3 SYT9 TRIM9 VAMP2 VAMP7 VAMP8 WASHC3 ZDHHC17	8 interacting genes: APP EBI3 GABARAPL2 NAPA NSF SNAP25 STX5 USO1
Entrez ID		6616	9527
HPRD ID		02637	04936
Ensembl ID		ENSG00000132639	ENSG00000108587
Uniprot IDs		P60880	E9PCW1 O95249
PDB IDs		1KIL 1XTG 2N1T 3DDA 3DDB 3RK2 3RK3 3RL0 3ZUR 5W7I 5W7J
Enriched GO Terms of Interacting Partners?
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