ZBTB10 and LSM4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZBTB10	LSM4
Description		zinc finger and BTB domain containing 10	LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	P-body Nucleus Nucleoplasm U6 SnRNP Cytosol Membrane Protein-containing Complex Neuron Projection U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	RNA Binding Protein Binding U6 SnRNA Binding PH Domain Binding
	Biological Process		Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Cytoplasmic MRNA Processing Body Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31361310 30929738 27182965 29273806) Asthma (adult onset) ( 31036433 30929738) Asthma (childhood onset) ( 31036433 30929738) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 22197932 26482879) Basal cell carcinoma ( 27539887) Body mass index ( 28892062 30271922 25673413) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Hypothyroidism ( 22493691) Late-onset myasthenia gravis ( 26562150) Self-reported allergy ( 23817569) Self-reported risk-taking behaviour ( 30271922) Sex hormone-binding globulin levels ( 22829776) Urinary albumin-to-creatinine ratio ( 31511532)	Chronotype ( 30696823) Estimated glomerular filtration rate ( 30604766) Gastroesophageal reflux disease ( 31527586) Intraocular pressure ( 29617998) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252)
Interacting Genes		6 interacting genes: HRAS LSM4 MOB3C MORF4L1 MORF4L2 ZNF417	19 interacting genes: CALCOCO2 COX5B IKZF1 L3MBTL3 LSM1 LSM7 NMI PLEKHA5 PSTPIP1 RHOXF2 SLC22A2 SMIM14 SMN1 SMU1 SNRPE TOE1 TOP1 XRN1 ZBTB10
Entrez ID		65986	25804
HPRD ID		15689	06284
Ensembl ID		ENSG00000205189	ENSG00000130520
Uniprot IDs		Q96DT7 Q9H9H3	Q9Y4Z0 U3KQK1
PDB IDs			3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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