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BMPR2 and TRPC1
Number of citations of the paper that reports this interaction (PubMedID
15188402
)
31
Data Source:
HPRD
(in vitro)
BMPR2
TRPC1
Description
bone morphogenetic protein receptor type 2
transient receptor potential cation channel subfamily C member 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleoplasm
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Caveola
Adherens Junction
Basal Plasma Membrane
Cell Surface
Postsynaptic Density
Apical Plasma Membrane
Dendrite
Neuronal Cell Body
Receptor Complex
Spanning Component Of Plasma Membrane
Cell
Plasma Membrane
Integral Component Of Plasma Membrane
Cation Channel Complex
Receptor Complex
Molecular Function
Protein Serine/threonine Kinase Activity
Transforming Growth Factor Beta-activated Receptor Activity
Protein Binding
ATP Binding
Activin Receptor Activity, Type II
Growth Factor Binding
BMP Binding
Cadherin Binding
Metal Ion Binding
BMP Receptor Activity
Protein Tyrosine Kinase Binding
Signaling Receptor Binding
Cation Channel Activity
Calcium Channel Activity
Protein Binding
Store-operated Calcium Channel Activity
ATPase Binding
Inositol 1,4,5 Trisphosphate Binding
Biological Process
Blood Vessel Development
Mesoderm Formation
Maternal Placenta Development
Endothelial Cell Proliferation
Positive Regulation Of Endothelial Cell Proliferation
Vasculature Development
Lymphangiogenesis
Blood Vessel Remodeling
Chondrocyte Development
Negative Regulation Of Systemic Arterial Blood Pressure
Outflow Tract Septum Morphogenesis
Outflow Tract Morphogenesis
Aortic Valve Development
Pulmonary Valve Development
Atrioventricular Valve Morphogenesis
Mitral Valve Morphogenesis
Tricuspid Valve Morphogenesis
Endocardial Cushion Development
Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis
Transcription By RNA Polymerase II
Protein Phosphorylation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Brain Development
Cellular Response To Starvation
Anterior/posterior Pattern Specification
Positive Regulation Of Endothelial Cell Migration
Positive Regulation Of Epithelial Cell Migration
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Regulation Of Lung Blood Pressure
Proteoglycan Biosynthetic Process
Negative Regulation Of Cell Growth
Positive Regulation Of Bone Mineralization
BMP Signaling Pathway
Positive Regulation Of BMP Signaling Pathway
Activin Receptor Signaling Pathway
Regulation Of Cell Proliferation
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Ossification
Negative Regulation Of Vasoconstriction
Positive Regulation Of Transcription By RNA Polymerase II
Lung Alveolus Development
Cardiac Muscle Tissue Development
Positive Regulation Of Axon Extension Involved In Axon Guidance
Limb Development
Endochondral Bone Morphogenesis
Ventricular Septum Morphogenesis
Atrial Septum Morphogenesis
Lymphatic Endothelial Cell Differentiation
Artery Development
Venous Blood Vessel Development
Positive Regulation Of Cartilage Development
Retina Vasculature Development In Camera-type Eye
Pharyngeal Arch Artery Morphogenesis
Cellular Response To Growth Factor Stimulus
Cellular Response To BMP Stimulus
Endothelial Cell Apoptotic Process
Negative Regulation Of Chondrocyte Proliferation
Semi-lunar Valve Development
Negative Regulation Of DNA Biosynthetic Process
Calcium Ion Transport
Manganese Ion Transport
Melanin Biosynthetic Process
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Regulation Of Cytosolic Calcium Ion Concentration
Response To Calcium Ion
Calcium Ion Transmembrane Transport
Regulation Of Cardiac Conduction
Pathways
Signaling by BMP
TRP channels
Role of second messengers in netrin-1 signaling
Ion homeostasis
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS
Intelligence (MTAG) (
29326435
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
Urate levels (
23263486
)
Interacting Genes
51 interacting genes:
ACTR8
ACVR1
ACVR1B
ARSA
BMP10
BMP2
BMP4
BMP6
BMP7
BMPR1A
BMPR1B
C4BPA
CCDC89
CES1
CRYAB
CTBP1
DYNLT1
FHL2
FOXL1
FRS3
GDF2
GDF5
GDF6
GDF9
HNRNPR
INHBB
LIMK1
LMX1A
LSM10
LSP1
MAP3K8
MAPK8
MERTK
MOS
NBEA
NOP56
PDZRN3
PMPCA
PPP1CC
PRKCB
RABGGTA
SULT1E1
TDGF1
TGFBR1
TOPBP1
TRIB3
TRPC1
TSR1
TUBB
TUBB4A
TWF1
14 interacting genes:
BMPR2
CAV1
GRIA1
HOMER1
HOMER3
ITPR2
ITPR3
MDFI
MX1
PKD2
RHOA
TRPC3
TRPC4
TRPC5
Entrez ID
659
7220
HPRD ID
02880
11894
Ensembl ID
ENSG00000204217
ENSG00000144935
Uniprot IDs
Q13873
P48995
PDB IDs
2HLQ
3G2F
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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