SLC34A1 and MAST2

Number of citations of the paper that reports this interaction (PubMedID 11099500)
47

Data Source:
HPRD (two hybrid)

		SLC34A1	MAST2
Description		solute carrier family 34 member 1	microtubule associated serine/threonine kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Cell Nucleoplasm Endosome Cytosol Plasma Membrane Integral Component Of Plasma Membrane Brush Border Cell Surface Apical Plasma Membrane Nuclear Speck Brush Border Membrane Vesicle Membrane Raft Perinuclear Region Of Cytoplasm Mitotic Spindle	Cytoplasm Plasma Membrane Microtubule Cytoskeleton
	Molecular Function	Sodium:phosphate Symporter Activity Protein Binding PDZ Domain Binding Identical Protein Binding Protein-containing Complex Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Phosphatase Binding
	Biological Process	Ossification Kidney Development Phosphate Ion Transport Glycoprotein Metabolic Process Response To Lead Ion Cellular Phosphate Ion Homeostasis Response To Magnesium Ion Response To Estradiol Response To Vitamin A Phosphate Ion Transmembrane Transport Response To Potassium Ion Indole Metabolic Process Response To Drug Cellular Protein Metabolic Process Sodium-dependent Phosphate Transport Positive Regulation Of Membrane Potential Response To Cadmium Ion Response To Mercury Ion Phosphate Ion Homeostasis Response To Growth Hormone Cellular Response To Metal Ion Cellular Response To Parathyroid Hormone Stimulus Tricarboxylic Acid Metabolic Process Cellular Response To Staurosporine Response To Thyroid Hormone Dentinogenesis Sodium Ion Import Across Plasma Membrane Gentamycin Metabolic Process Arsenate Ion Transmembrane Transport Positive Regulation Of Sodium-dependent Phosphate Transport Positive Regulation Of Phosphate Transmembrane Transport	Protein Phosphorylation Cytoskeleton Organization Peptidyl-serine Phosphorylation Intracellular Signal Transduction Regulation Of Interleukin-12 Biosynthetic Process Spermatid Differentiation
Pathways		Type II Na+/Pi cotransporters Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1) Surfactant metabolism
Drugs
Diseases		Nephrolithiasis/osteoporosis, hypophosphatemic
GWAS		Activated partial thromboplastin time ( 22703881) Calcium levels ( 24068962) Chronic kidney disease ( 31152163 26831199 20383146) Creatinine levels ( 31015462 28270201 29403010) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Hematocrit ( 29403010) Inflammatory bowel disease ( 28067908) Kidney stones ( 26272126 31729369) Nephrolithiasis ( 22396660) Phosphorus levels ( 29403010) Red blood cell count ( 29403010) Serum parathyroid hormone levels ( 27927781) Ulcerative colitis ( 28067908) Urinary electrolytes (magnesium/calcium ratio) ( 27915449) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Blood protein levels ( 28240269) Body mass index ( 25673413) Granulocyte count ( 27863252) Iron status biomarkers (total iron binding capacity) ( 28334935) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Red blood cell count ( 27863252) Reticulocyte count ( 27863252) Sum basophil neutrophil counts ( 27863252)
Interacting Genes		11 interacting genes: BSPRY FHL2 HPCAL1 HSP90AA1 HSP90AB1 MAST2 PDZK1 PEX19 SLC9A3R1 SLC9A3R2 YIF1A	17 interacting genes: APP CDHR2 DYNLL1 PTEN RPS27A RPS6KA1 SH3GL2 SLC34A1 SLC9A3 SMN1 SNTB2 SRPK2 STK36 SUMO2 TK1 TRAF2 TRAF6
Entrez ID		6569	23139
HPRD ID		08918	11294
Ensembl ID		ENSG00000131183	ENSG00000086015
Uniprot IDs		A0A024R7R9 Q06495 Q7Z725 Q86VN6	Q6P0Q8
PDB IDs			2KQF 2KYL
Enriched GO Terms of Interacting Partners?
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