INTS3 and ZBTB14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		INTS3	ZBTB14
Description		integrator complex subunit 3	zinc finger and BTB domain containing 14
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Integrator Complex SOSS Complex	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome
	Molecular Function	Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	DNA Repair Cellular Response To DNA Damage Stimulus Mitotic Cell Cycle Checkpoint Response To Ionizing Radiation SnRNA Processing SnRNA Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Heart Valve Development Cardiac Septum Development Negative Regulation Of Transcription, DNA-templated Coronary Vasculature Development
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS			Cerebral amyloid deposition (PET imaging) ( 26252872)
Interacting Genes		5 interacting genes: APP CTDP1 INTS6 NABP2 ZBTB14	37 interacting genes: AP1M1 ATP5PO BAZ2B BYSL CBX8 CDK16 CDKL3 CEP19 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 NAA10 PIN1 PNKP POLR2L PRMT1 RNPS1 RPL9 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TXN2 ZBTB21 ZCCHC10 ZMAT2
Entrez ID		65123	7541
HPRD ID		08644	03674
Ensembl ID		ENSG00000143624	ENSG00000198081
Uniprot IDs		Q68E01	B2R850 O43829
PDB IDs		4OWT 4OWW 4OWX
Enriched GO Terms of Interacting Partners?
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