CENPH and CENPK

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		CENPH	CENPK
Description		centromere protein H	centromere protein K
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Nucleolus Cytosol	Condensed Nuclear Chromosome Inner Kinetochore Nucleoplasm Cytosol
	Molecular Function	Protein Binding Kinetochore Binding	Protein Binding
	Biological Process	Mitotic Spindle Organization Chromosome Segregation CENP-A Containing Nucleosome Assembly Kinetochore Assembly Kinetochore Organization	Mitotic Sister Chromatid Segregation CENP-A Containing Nucleosome Assembly Kinetochore Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Diverticular disease ( 30177863)
Interacting Genes		5 interacting genes: CENPK KIF2C MTAP NDC80 NUF2	6 interacting genes: AP1G2 CENPH HSPB1 MRFAP1L1 PCBD2 SOX6
Entrez ID		64946	64105
HPRD ID		12029	13323
Ensembl ID		ENSG00000153044	ENSG00000123219
Uniprot IDs		A0A0S2Z5T0 Q9H3R5	D6RHD3 Q9BS16
PDB IDs
Enriched GO Terms of Interacting Partners?
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