TTC23 and SELENOS

		TTC23	SELENOS
Description		tetratricopeptide repeat domain 23	selenoprotein S
Image		No pdb structure
GO Annotations	Cellular Component	Cilium	Cell Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle Derlin-1-VIMP Complex Derlin-1 Retrotranslocation Complex
	Molecular Function	Protein Binding	Protein Binding Antioxidant Activity Enzyme Binding Signaling Receptor Activity ATPase Binding Ubiquitin-specific Protease Binding
	Biological Process	Positive Regulation Of Smoothened Signaling Pathway	Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Gluconeogenesis ER Overload Response Response To Glucose Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Cellular Response To Insulin Stimulus Cellular Response To Oxidative Stress Establishment Of Protein Localization Cell Redox Homeostasis Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Glucose Import Negative Regulation Of Inflammatory Response Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process Response To Redox State Cellular Response To Lipopolysaccharide Regulation Of Nitric Oxide Metabolic Process Cellular Oxidant Detoxification Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Macrophage Apoptotic Process
Pathways			E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Interacting Genes		23 interacting genes: ALAS1 APP BHLHE40 CCNDBP1 CNTROB CREBZF GOLGA2 HTT KRT31 KRT40 KRTAP10-3 LDOC1 LZTS2 MAGED1 MDFI PNMA5 SELENOS SPAG5 SSX2IP TADA2A TRIM10 TRIM54 ZDHHC17	24 interacting genes: BLZF1 CD180 CELF4 DERL1 EIF2AK1 ETV7 GTF2IRD1 KLHDC2 KPNB1 LIMK1 LINS1 LRRK1 MFHAS1 NCBP1 OR4F4 SAA1 SNRPA1 SRPK2 SYNM TARS3 TM2D3 TTC23 VCP ZBTB33
Entrez ID		64927	55829
HPRD ID		07777	12133
Ensembl ID		ENSG00000103852	ENSG00000131871
Uniprot IDs		Q5W5X9	Q6GYA4 Q9BQE4
PDB IDs			2Q2F 5KIU 5KIY 6DO4
Enriched GO Terms of Interacting Partners?
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