BCL11B and NR2F1

Number of citations of the paper that reports this interaction (PubMedID 10744719)
83

Data Source:
HPRD (two hybrid, in vitro)

		BCL11B	NR2F1
Description		BAF chromatin remodeling complex subunit BCL11B	nuclear receptor subfamily 2 group F member 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Neuron Projection	Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Transcription Coactivator Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Retinoic Acid-responsive Element Binding
	Biological Process	Keratinocyte Development Epithelial Cell Morphogenesis Regulation Of Transcription, DNA-templated Multicellular Organism Development Negative Regulation Of Cell Proliferation Regulation Of Keratinocyte Proliferation Regulation Of Lipid Metabolic Process Striatal Medium Spiny Neuron Differentiation Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Post-embryonic Camera-type Eye Development T Cell Differentiation In Thymus T Cell Receptor V(D)J Recombination Hematopoietic Stem Cell Migration Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Apoptotic Process Positive T Cell Selection Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Alpha-beta T Cell Differentiation Thymus Development Olfactory Bulb Axon Guidance Lymphoid Lineage Cell Migration Into Thymus	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Negative Regulation Of Neuron Projection Development Cell Differentiation Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development
Pathways			Nuclear Receptor transcription pathway
Drugs			beta-Naphthoflavone
Diseases
GWAS		Adventurousness ( 30643258) Airway wall thickness ( 25517131) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Aortic stiffness ( 22068335) Bipolar disorder ( 31043756) Corneal curvature ( 22969067) Diastolic blood pressure night-to-day ratio in hypertension ( 29973135) Metabolite levels ( 23823483) Schizophrenia ( 28991256 25056061 29483656 30285260) Staphylococcus aureus infection ( 24847357) Systolic blood pressure night-to-day ratio in hypertension ( 29973135)
Interacting Genes		9 interacting genes: CBX5 MBD3 MTA2 NR2F1 NR2F2 RBBP4 RBBP7 SP1 SUV39H1	23 interacting genes: AHR BCL11A BCL11B CBX5 COPS2 EEF1D ESR1 GTF2B HNF4A ISL1 MAP6 MCPH1 NCOA1 NCOA2 NCOA3 NCOR2 NSD1 PFDN1 PHB2 POU2F2 RXRA SP1 THRA
Entrez ID		64919	7025
HPRD ID		05950	00584
Ensembl ID		ENSG00000127152	ENSG00000175745
Uniprot IDs		L8B567 L8B7P7 L8B862 L8B8F6 Q9C0K0	P10589
PDB IDs			2EBL
Enriched GO Terms of Interacting Partners?
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