RMND5A and MAEA

Number of citations of the paper that reports this interaction (PubMedID 29911972)
6

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		RMND5A	MAEA
Description		required for meiotic nuclear division 5 homolog A	macrophage erythroblast attacher, E3 ubiquitin ligase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm GID Complex	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Spindle Actomyosin Contractile Ring Cytoskeleton Integral Component Of Plasma Membrane Nuclear Matrix GID Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding	Actin Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Ubiquitin-dependent Protein Catabolic Process Cytoskeleton Organization Cell Cycle Cell Adhesion Regulation Of Mitotic Cell Cycle Protein Ubiquitination Negative Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Erythrocyte Maturation Negative Regulation Of Gluconeogenesis Enucleate Erythrocyte Development Cell Division
Pathways
Drugs			WF10
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Obesity-related traits ( 23251661) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969 26818947 23945395 22158537 30718926 28869590)
Interacting Genes		5 interacting genes: APP MAEA MEOX2 SMAD9 VKORC1	12 interacting genes: ARMC8 GID4 GID8 MKLN1 MYOC RANBP10 RMND5A UBE2D3 UBE2H UBE2R2 WDR26 YPEL5
Entrez ID		64795	10296
HPRD ID		07841	08427
Ensembl ID		ENSG00000153561	ENSG00000090316
Uniprot IDs		Q9H871	B3KRN7 B4DJP8 B4DQT1 B4DVN3 D6RIB6 Q7L5Y9
PDB IDs
Enriched GO Terms of Interacting Partners?
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