SIAH1 and AFF1

  • Number of citations of the paper that reports this interaction (PubMedID 15221006)
  • 25
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (two hybrid, in vivo, in vitro)

SIAH1

AFF1

Description siah E3 ubiquitin protein ligase 1 AF4/FMR2 family member 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (cognitive decline) ( 23535033)
  • Basophil percentage of granulocytes ( 27863252)
  • Basophil percentage of white cells ( 27863252)
  • Bulimia nervosa ( 23568457)
  • Diastolic blood pressure ( 28234671)
  • Eyebrow thickness ( 26926045)
  • HDL cholesterol levels ( 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Heel bone mineral density ( 30598549 28869591)
  • Hematocrit ( 29403010 27863252)
  • Hemoglobin ( 29403010)
  • Hemoglobin concentration ( 27863252)
  • Mean corpuscular hemoglobin ( 29403010 27863252)
  • Mean corpuscular volume ( 29403010 27863252)
  • Mean platelet volume ( 27863252)
  • Medication use (thyroid preparations) ( 31015401)
  • Metabolic syndrome ( 31589552)
  • Multiple sclerosis ( 31604244)
  • Red blood cell count ( 27863252)
  • Systemic lupus erythematosus ( 22291604)
  • Total bilirubin levels ( 29403010)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 20864672 30275531 25961943 20686565)
  • White blood cell count (basophil) ( 29403010 27863252)
Interacting Genes 141 interacting genes: AASDHPPT AFF1 AFF4 APC AQP1 ARMC9 ATN1 ATXN7 AXIN1 BAG1 BCL6 CACYBP CAPG CCDC198 CDC23 CDC34 CDK5R1 DAB1 DCC DDX41 DNAJC15 DNALI1 EEF1D EIF3J ELL2 EXOC3-AS1 FAM90A1 FLI1 FZD9 GAPDH GDPD5 GRM5 H4-16 HIF1AN HIPK2 HIPK3 INHA IQCN KATNAL1 KCNJ10 KHDRBS3 KIAA0319L KIAA1217 KIF1B KIF22 KIFC3 KLF10 LACTB2 LMNA MAB21L1 MAP3K5 MAPK12 MAPKBP1 MAPRE3 MOB3C MTIF3 MX1 MYD88 NANOS2 NANOS3 NECTIN2 NELFA NOL6 NTAQ1 NUMB NUMBL OPRM1 OTUB2 PARD6B PEG10 PEG3 PFKM PHC1 PHC2 PIAS2 PIAS3 PIMREG PKD1 POU2AF1 PRPF31 PRR20A PTPMT1 PUF60 PYGB QRICH1 RAB33A RAD51AP1 RAD54L2 RAPH1 RBBP8 RPL27A RPS19BP1 RXRB SDCBP SH3RF1 SLC9A3R2 SNCAIP SPATA4 SPATC1L SYP SYT7 TBC1D22B TERF2 TFDP1 TMEM43 TNK2 TOLLIP TP53BP2 TRIM23 TRIM27 TRIM7 TRIM8 TUBA1A TUBA1B TUBA3C TUBA4A TUBA8 TXN UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2I UBE2K UBE2L6 UBE2N UBE2V2 UPP2 USP19 UXT VAV1 ZBP1 ZCCHC10 ZCCHC13 ZFYVE21 ZMAT3 ZNF148 ZNF512B ZNF671 ZYX 9 interacting genes: H3-4 MLLT1 MLLT3 NT5E SASH1 SIAH1 SIAH2 SMAD9 TBCA
Entrez ID 6477 4299
HPRD ID 03736 08871
Ensembl ID ENSG00000196470 ENSG00000172493
Uniprot IDs Q8IUQ4 B4DJU9 P51825 Q14C88
PDB IDs 2A25 4C9Z 4CA1 4I7B 4I7C 4I7D 4X3G 5WZZ 2LM0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?