SHC1 and DDR1

  • Number of citations of the paper that reports this interaction (PubMedID 10783152)
  • 7
  • Data Source:
  • HPRD (in vitro, in vivo)

SHC1

DDR1

Description SHC adaptor protein 1 discoidin domain receptor tyrosine kinase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related macular degeneration ( 23455636)
  • Arterial stiffness index ( 31235810)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • HIV-1 control ( 20041166)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Microalbuminuria in type 1 diabetes ( 31537649)
  • Response to hepatitis B vaccine ( 29534301)
  • Rosacea symptom severity ( 29771307)
  • Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848)
  • Schizophrenia ( 30285260)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Takayasu arteritis ( 25604533)
  • Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
  • Ulcerative colitis ( 20848476)
Interacting Genes 137 interacting genes: ALK AP2A1 AP2A2 APP AXL BCL3 BCR C11orf58 CALCOCO2 CALD1 CBL CBLB CBLC CD22 CD247 CD3E CD81 CDH5 CEACAM1 CRK CRKL CSF1R CSF2RB CSF3R CSK DAG1 DDR1 DDR2 DOK1 DUSP23 EGFR EPHA2 EPOR EPS8 ERBB2 ERBB3 ERBB4 ESR1 FAM118B FCGR2A FCGR3A FGFR1 FGFR2 FLT1 FLT4 FYN GAB1 GAB2 GEMIN7 GH1 GHR GRAP GRAP2 GRB2 GRB7 HMOX2 IGF1R IL2 IL2RB IL2RG IL4R IL6ST ILK INPP5D INPPL1 INSR IRS1 IRS2 ITGB3 ITGB4 JAK2 KDR KRT18 LCK LCP2 LRP1 LTK LYN MAP4K1 MAPK1 MAPK14 MAPK6 MAPK8 MAPKAPK2 MET MME MPL MRPL44 MST1R NGFR NPM1 NTRK1 NTRK2 NTRK3 NUDT21 OSGEP PAG1 PAK1 PDGFRB PIK3C2B PIK3R1 PIK3R2 PLCG1 PLCG2 PLPP3 PLSCR1 PPP2R5A PRKCA PRKCD PRKRA PTK2 PTK2B PTPN11 PTPN12 PTPN2 PTPN6 RAPGEF1 RASA1 RET SH2B2 SHCBP1 SOS1 SOS2 SP1 SRC STAT5A STAT5B SUV39H2 SYK TEC TEK TPR TRIM15 UBASH3B VAV1 VAV3 ZAP70 19 interacting genes: BEND5 BRD2 COL11A1 COL2A1 COL3A1 COL5A2 ERBB2 FRS2 MAPK6 NCK2 NUDT3 PLCG1 PTPN11 RGS2 SHC1 SNAPIN SNRNP40 TM4SF1 TTR
Entrez ID 6464 780
HPRD ID 02780 02678
Ensembl ID ENSG00000160691 ENSG00000204580
Uniprot IDs P29353 A0A024RCJ0 A0A024RCL1 A0A024RCQ1 A0A0A0MSX3 Q08345 Q96T61 Q96T62
PDB IDs 1MIL 1N3H 1OY2 1QG1 1SHC 1TCE 1WCP 2L1C 4JMH 4XWX 5CZI 6DM4 3ZOS 4AG4 4BKJ 4CKR 5BVK 5BVN 5BVO 5BVW 5FDP 5FDX 6BRJ 6BSD 6FEW 6FEX 6FIL 6FIN 6FIO 6FIQ 6GWR 6HP9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?