SHBG and APEH

Number of citations of the paper that reports this interaction (PubMedID 15862967)
3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SHBG	APEH
Description		sex hormone binding globulin	acylaminoacyl-peptide hydrolase
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Exosome	Extracellular Region Cytosol Nuclear Membrane Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Steroid Binding Androgen Binding Protein Binding	RNA Binding Serine-type Endopeptidase Activity Protein Binding Omega Peptidase Activity Identical Protein Binding
	Biological Process		Translational Termination Proteolysis Neutrophil Degranulation Amyloid-beta Metabolic Process
Pathways			Neutrophil degranulation Eukaryotic Translation Termination
Drugs		Masoprocol Diethylstilbestrol Levonorgestrel Progesterone Spironolactone Toremifene Estrone Tamoxifen Clomifene Dienestrol Ethinyl Estradiol Hesperetin Zinc Genistein Naringenin Quercetin 4'-Hydroxyflavanone Afimoxifene Estriol Phenolphthalein Equol
Diseases
GWAS		Androgen levels ( 22936694) Blood protein levels ( 30072576) Heel bone mineral density ( 30598549) Hormone measurements ( 24049095) Medication use (calcium channel blockers) ( 31015401) Protein quantitative trait loci ( 18464913) Red cell distribution width ( 27863252) Sex hormone levels ( 26014426) Sex hormone-binding globulin levels ( 22675492 22829776) Testosterone levels ( 21998597) Uterine fibroids ( 31649266)	Blood protein levels ( 29875488 28240269) Body mass index ( 26426971) Crohn's disease ( 28067908) Extremely high intelligence ( 29520040) Feeling tense ( 29500382) Feeling worry ( 29500382) Household income ( 31844048) Inflammatory bowel disease ( 28067908) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Ulcerative colitis ( 28067908 21297633)
Interacting Genes		62 interacting genes: A2M ACP3 ACTA2 ACTB ACTG2 AK2 AKR1B1 AP1B1 AP2A1 APEH APOBEC3C APOD ASB16-AS1 ATP5F1A AZGP1 C9orf24 CD177 CEP192 CLDN4 CLEC4G COL1A2 CTSD DDX3Y DES DSTN EEF1A1 EIF3E EIF3F FLNA FLOT1 FYTTD1 GRB2 HDHD5 HYI JMJD7-PLA2G4B KLK4 MPDU1 MT1F MT1G MT2A MXD4 NOMO1 PACSIN2 PKM PLA2G4A PLP2 PSTPIP1 PSTPIP2 PTGDS RMND5B SEMA3F SLC37A1 SLC37A4 SNAPIN SNRNP70 SORD SRF SRI TINAGL1 UBE2O UBE3A ZC3H12A	5 interacting genes: IST1 LGALS8 SHBG TMEM62 UBA5
Entrez ID		6462	327
HPRD ID		01646	00034
Ensembl ID		ENSG00000129214	ENSG00000164062
Uniprot IDs		B0FWH2 B0FWH8 B4DYU0 I3L145 P04278	P13798
PDB IDs		1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW
Enriched GO Terms of Interacting Partners?
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