SELE and SELPLG

Number of citations of the paper that reports this interaction (PubMedID 8621728)
60

Data Source:
HPRD (in vivo, in vitro)

		SELE	SELPLG
Description		selectin E	selectin P ligand
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Caveola Clathrin-coated Pit Cortical Cytoskeleton Membrane Raft Perinuclear Region Of Cytoplasm	Uropod Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Plasma Membrane Raft
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Sialic Acid Binding Phospholipase Binding Metal Ion Binding Oligosaccharide Binding	Virus Receptor Activity Signaling Receptor Binding Protein Binding
	Biological Process	Positive Regulation Of Receptor Internalization Leukocyte Migration Involved In Inflammatory Response Inflammatory Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Activation Of Phospholipase C Activity Calcium-mediated Signaling Actin Filament-based Process Response To Lipopolysaccharide Response To Tumor Necrosis Factor Regulation Of Inflammatory Response Leukocyte Migration Leukocyte Tethering Or Rolling Response To Interleukin-1 Positive Regulation Of Leukocyte Tethering Or Rolling	Cell Adhesion Viral Entry Into Host Cell Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6
Pathways		Cell surface interactions at the vascular wall	Cell surface interactions at the vascular wall
Drugs		Carvedilol N-acetyl-alpha-neuraminic acid
Diseases
GWAS		Blood protein levels ( 30072576) Inflammatory bowel disease ( 26192919)	Acne (severe) ( 24927181) Blood protein levels ( 30072576) Conduct disorder (symptom count) ( 20585324)
Interacting Genes		14 interacting genes: ACTA2 ACTN2 CD44 FLNA GLG1 LGALS3BP PLCG1 PTK2 PTPN11 PXN SELL SELPLG SERPING1 VCL	15 interacting genes: BACE1 CIT CTSG ECSIT GALNT4 MAGEA1 MSN SELE SELL SELP SYK TNIP1 TPST1 TPST2 VCAN
Entrez ID		6401	6404
HPRD ID		00566	02845
Ensembl ID		ENSG00000007908	ENSG00000110876
Uniprot IDs		P16581	Q14242
PDB IDs		1ESL 1G1T 1KJA 4C16 4CSY 6EYI 6EYJ 6EYK	1G1S
Enriched GO Terms of Interacting Partners?
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