BICD1 and CPNE4

Number of citations of the paper that reports this interaction (PubMedID 12522145)
33

Data Source:
HPRD (in vitro, two hybrid)

		BICD1	CPNE4
Description		BICD cargo adaptor 1	copine 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Centrosome Cytosol Cytoskeleton Cytoplasmic Microtubule Membrane Cytoplasmic Vesicle Tubulin Complex Perinuclear Region Of Cytoplasm Host Cell Viral Assembly Compartment	Plasma Membrane Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Rab GTPase Binding Protein Kinase Binding Proteinase Activated Receptor Binding Dynactin Binding Dynein Intermediate Chain Binding Dynein Complex Binding	Protein Binding Calcium-dependent Phospholipid Binding
	Biological Process	RNA Processing Intracellular MRNA Localization Anatomical Structure Morphogenesis Viral Process Protein Localization To Organelle Stress Granule Assembly Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Microtubule Cytoskeleton Organization Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center Negative Regulation Of Phospholipase C Activity Regulation Of Proteinase Activated Receptor Activity Negative Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Localization To Centrosome	Cellular Response To Calcium Ion
Pathways		COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Emphysema-related traits ( 20709820) Fourth ventricle volume ( 31530798) Normalized brain volume ( 19010793) Obesity-related traits ( 23251661) Pancreatic cancer ( 20686608)	Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Amyotrophic lateral sclerosis ( 22959728) Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals ( 22959728) Body mass index ( 31453325 28892062 25673413) Body mass index variance ( 31453325) Circulating leptin levels in high cardiovascular risk ( 31766143) Coronary artery aneurysm in Kawasaki disease ( 27171184) Intracranial aneurysm ( 29531279) Iron status biomarkers (total iron binding capacity) ( 28334935) Metabolic syndrome ( 31589552) Motion sickness ( 25628336) Neutrophil count ( 21507922)
Interacting Genes		12 interacting genes: ALPI CPNE4 DCTN1 DCTN2 DISC1 DYNC1I1 GSK3A GSK3B MAPK14 NIN RAB6A STAT3	16 interacting genes: ACTB BCOR BICD1 CCDC22 CEP162 CPNE1 MAP2K1 MYCBP PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 UBE2M UBE2O
Entrez ID		636	131034
HPRD ID		03730	05017
Ensembl ID		ENSG00000151746	ENSG00000196353
Uniprot IDs		Q96G01	B7Z370 Q4G168 Q96A23
PDB IDs
Enriched GO Terms of Interacting Partners?
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