SAFB and TAF15

Number of citations of the paper that reports this interaction (PubMedID 15066997)
24

Data Source:
HPRD (in vivo, in vitro)

		SAFB	TAF15
Description		scaffold attachment factor B	TATA-box binding protein associated factor 15
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Double-stranded DNA Binding RNA Binding Protein Binding Sequence-specific DNA Binding	DNA Binding Transcription Coregulator Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Metal Ion Binding
	Biological Process	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Intracellular Estrogen Receptor Signaling Pathway Regulation Of Growth Hormone Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Processing	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter RNA Splicing Positive Regulation Of Transcription, DNA-templated MRNA Stabilization Regulation Of Signal Transduction By P53 Class Mediator
Pathways		SUMOylation of transcription cofactors	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases			Extraskeletal myxoid chondrosarcoma
GWAS			Blood protein levels ( 28240269) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		22 interacting genes: ABHD16A CDC37 CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R MAP1LC3B NCOR1 POLR2A SAFB2 SREK1 SRPK1 SRPK2 SRSF9 TAF15 TJP2	22 interacting genes: ARID1A CACNA1A H2AC20 H3-4 H3C1 H4C14 POLR2C POLR2E POLR2G PRMT8 SAFB SF1 SMARCA4 SMARCC1 SMARCC2 TAF1 TAF12 TAF13 TAF5 TAF7 YWHAG ZNF384
Entrez ID		6294	8148
HPRD ID		04205	09031
Ensembl ID		ENSG00000160633	ENSG00000270647
Uniprot IDs		B7Z2F6 B7ZLP5 Q15424	Q92804
PDB IDs			2MMY
Enriched GO Terms of Interacting Partners?
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