S100B and DNAJC30

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		S100B	DNAJC30
Description		S100 calcium binding protein B	DnaJ heat shock protein family (Hsp40) member C30
Image
GO Annotations	Cellular Component	Ruffle Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Neuronal Cell Body Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Tau Protein Binding Calcium-dependent Protein Binding RAGE Receptor Binding	Protein Binding
	Biological Process	Axonogenesis Central Nervous System Development Learning Or Memory Memory Positive Regulation Of Cell Proliferation Regulation Of Cell Shape Positive Regulation Of Myelination Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Neuronal Synaptic Plasticity Astrocyte Differentiation Response To Glucocorticoid Response To Methylmercury Long-term Synaptic Potentiation Cellular Response To Hypoxia Negative Regulation Of Skeletal Muscle Cell Differentiation	ATP Biosynthetic Process Brain Development Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		Nuclear signaling by ERBB4 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation
Drugs		Olopatadine Calcium N-Formylmethionine Arundic acid (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide Calcium Citrate Calcium Phosphate
Diseases
GWAS		Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Lymphocyte counts ( 22286170)	Blood protein levels ( 29875488)
Interacting Genes		42 interacting genes: ADTRP AGER AGTRAP AHNAK ANXA6 BCL2L2 CACYBP CALM1 CAPZA1 CEP20 CT45A5 DES DNAJC30 FBXO7 FBXW5 GFAP GUCY2D IMP4 IMPA1 IQGAP1 MAL2 MAPT MDM2 MDM4 NDRG1 NKAPD1 PCNT PGM1 RABAC1 S100A1 S100A11 S100A2 S100A6 S100P SPG21 STK38 SUGT1 TMEM159 TMEM239 TNIP1 TP53 VAV1	6 interacting genes: APP CREB3 EXOSC6 FBXO7 LMNA S100B
Entrez ID		6285	84277
HPRD ID		01505	10303
Ensembl ID		ENSG00000160307	ENSG00000176410
Uniprot IDs		A0A0S2Z4C5 P04271	B3KSU4 Q96LL9
PDB IDs		1MQ1 1UWO 2H61 2M49 2PRU 3CZT 3D0Y 3D10 3HCM 4XYN 5CSF 5CSI 5CSJ 5CSN 5D7F	2YUA
Enriched GO Terms of Interacting Partners?
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