RXRG and MAP4

Number of citations of the paper that reports this interaction (PubMedID 15604093)
54

Data Source:
HPRD (two hybrid)

		RXRG	MAP4
Description		retinoid X receptor gamma	microtubule associated protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex	Cell Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Postsynaptic Density Microtubule Cytoskeleton Axon Neuron Projection Mitotic Spindle
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Retinoic Acid-responsive Element Binding	RNA Binding Structural Molecule Activity Protein Binding Microtubule Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Response To Retinoic Acid Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Anatomical Structure Development	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Neuron Projection Development Microtubule Sliding Establishment Of Spindle Orientation Cell Division Negative Regulation Of Non-motile Cilium Assembly
Pathways		Nuclear Receptor transcription pathway Signaling by Retinoic Acid
Drugs		Adapalene Bexarotene Rosiglitazone Acitretin Alitretinoin Tretinoin Etretinate Bezafibrate Phthalic Acid Doconexent	Paclitaxel Docetaxel Artenimol
Diseases
GWAS		AIDS ( 19754311) Bipolar disorder (age of onset <21) or attention deficit hyperactivity disorder ( 27890468) Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Macular thickness ( 30535121) Menarche (age at onset) ( 27182965 21102462 29773799 25231870) Metabolite levels ( 23823483) Personality traits in bipolar disorder ( 21368711)	Blood pressure ( 21909110) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diastolic blood pressure ( 27841878 28739976 27618452) Mean arterial pressure ( 27618448) Medication use (calcium channel blockers) ( 31015401) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 28739976 27618452 30578418)
Interacting Genes		29 interacting genes: CAMK2B CEBPZ CHGB CREBBP DCK HOXD4 ITGB3BP LRSAM1 MAP4 MPPED2 NCOA6 NCOR2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR4A1 PNO1 PPARA PPARD PPARG RARA RARB RARG SRF THRA THRB VDR	22 interacting genes: CCNB1 CDC42 CDK1 CLASP1 ENO2 ERBIN GSK3B IL7R LDLR MARK1 MARK4 NOP58 NR1I3 POT1 RXRB RXRG SNTA1 SRPK2 STRBP TERF1 TUBB UBC
Entrez ID		6258	4134
HPRD ID		01579	01141
Ensembl ID		ENSG00000143171	ENSG00000047849
Uniprot IDs		A0A087WZ88 F1D8Q7 F1T097 P48443	P27816
PDB IDs		2GL8
Enriched GO Terms of Interacting Partners?
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