RPS24 and PAH

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RPS24	PAH
Description		ribosomal protein S24	phenylalanine hydroxylase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Small Ribosomal Subunit Membrane Cytosolic Small Ribosomal Subunit	Cytosol
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Translation Initiation Factor Binding	Phenylalanine 4-monooxygenase Activity Iron Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Erythrocyte Homeostasis Ribosomal Small Subunit Biogenesis	L-phenylalanine Catabolic Process Tyrosine Biosynthetic Process Cellular Amino Acid Biosynthetic Process Neurotransmitter Biosynthetic Process Catecholamine Biosynthetic Process Oxidation-reduction Process
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Phenylketonuria Phenylalanine metabolism
Drugs			L-Phenylalanine Sapropterin Norepinephrine Epinephrine Quinonoid 7,8-Tetrahydrobiopterin Beta(2-Thienyl)Alanine L-erythro-7,8-dihydrobiopterin D-norleucine Droxidopa
Diseases		Diamond-Blackfan anemia (DBA)	Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS		California verbal learning test score ( 31596458) Diverticular disease ( 30177863) Metabolite levels ( 23823483)	Amino acid levels ( 26068415) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood metabolite levels ( 24816252) Metabolite levels (small molecules and protein measures) ( 27005778) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		5 interacting genes: PAH PCBD1 PNISR STK17B TAF9	3 interacting genes: PCBD1 QDPR RPS24
Entrez ID		6229	5053
HPRD ID		03877	08943
Ensembl ID		ENSG00000138326	ENSG00000171759
Uniprot IDs		A0A2R8Y849 P62847	A0A024RBG4 P00439
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	1DMW 1J8T 1J8U 1KW0 1LRM 1MMK 1MMT 1PAH 1TDW 1TG2 2PAH 3PAH 4ANP 4PAH 5FII 5PAH 6HPO 6HYC 6N1K 6PAH
Enriched GO Terms of Interacting Partners?
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