RPS6 and PRKCSH

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RPS6	PRKCSH
Description		ribosomal protein S6	protein kinase C substrate 80K-H
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Endoplasmic Reticulum Cytosol Small Ribosomal Subunit Membrane Cytosolic Small Ribosomal Subunit Dendrite Cytoplasmic Ribonucleoprotein Granule Cell Body Ribonucleoprotein Complex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Glucosidase II Complex Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Protein Kinase Binding	Protein Kinase C Binding Calcium Ion Binding Protein Binding Ion Channel Binding Phosphoprotein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription TOR Signaling Ribosomal Small Subunit Biogenesis Glucose Homeostasis Positive Regulation Of Apoptotic Process	Protein Folding N-glycan Processing Intracellular Signal Transduction Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation mTORC1-mediated signalling SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Advanced glycosylation endproduct receptor signaling Post-translational protein phosphorylation Calnexin/calreticulin cycle
Drugs		Artenimol
Diseases			Polycystic liver disease
GWAS		Total cholesterol levels ( 29083408)	Presence of antiphospholipid antibodies ( 27098658) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		13 interacting genes: ATF4 FRS2 NDRG1 OLFM2 PAK2 PLA2G12A PRKACB PRKCSH PTEN RPS6KB1 RPS6KB2 STAU1 UPF2	10 interacting genes: ARL4D CANX ESR1 GANAB GBA3 GET4 PTPRC RGS2 RPS6 VDR
Entrez ID		6194	5589
HPRD ID		01592	03518
Ensembl ID		ENSG00000137154	ENSG00000130175
Uniprot IDs		A2A3R6 P62753	B4DJQ5 K7ELL7 P14314
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6F4P 6F4Q 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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