RINT1 and ZW10

Number of citations of the paper that reports this interaction (PubMedID 15029241)
79

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		RINT1	ZW10
Description		RAD50 interactor 1	zw10 kinetochore protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Dsl1/NZR Complex	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Cell Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Kinetochore Microtubule Cytosol Membrane Dsl1/NZR Complex RZZ Complex
	Molecular Function	Protein Binding	Protein Binding Centromeric DNA Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Cell Cycle Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Mitotic Metaphase Plate Congression Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Regulation Of Exit From Mitosis Protein Transport Protein Localization To Kinetochore Cell Division Meiotic Cell Cycle Protein-containing Complex Assembly
Pathways		COPI-dependent Golgi-to-ER retrograde traffic	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Parental longevity (father's attained age) ( 29227965)
Interacting Genes		55 interacting genes: ARNT2 BNIP3L C1orf109 CCDC121 CCDC146 CEP57L1 CSPP1 CWF19L2 DCX EPC1 FAM107A FAM110A FAM124B FAM161A FAM81B FAM90A1 FANCG GFI1B GRAP2 HDAC4 HGS LMO2 LSP1P3 MCM7 PCM1 PIK3R2 PIMREG PRPF31 PSTPIP1 RAD50 RB1 RBL1 RBL2 RBM41 RIBC1 RNF6 RSRC2 RTP5 SCNM1 SFR1 SGF29 SH2D4A SMARCB1 SMARCE1 SNW1 SPTBN1 STRN TEX9 TXLNA VPS37C XPNPEP1 ZNF655 ZNF688 ZNF697 ZW10	7 interacting genes: APP DCTN2 PIAS4 PTF1A RINT1 ZWILCH ZWINT
Entrez ID		60561	9183
HPRD ID		15250	04902
Ensembl ID		ENSG00000135249	ENSG00000086827
Uniprot IDs		Q6NUQ1	O43264
PDB IDs
Enriched GO Terms of Interacting Partners?
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