CCDC90B and PRDX5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCDC90B	PRDX5
Description		coiled-coil domain containing 90B	peroxiredoxin 5
Image
GO Annotations	Cellular Component	Mitochondrion Integral Component Of Membrane Mitochondrial Membrane	Extracellular Space Cell Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	RNA Polymerase III Regulatory Region DNA Binding Peroxidase Activity Protein Binding Thioredoxin Peroxidase Activity Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process		Apoptotic Process Inflammatory Response Response To Oxidative Stress Negative Regulation Of Transcription By RNA Polymerase III Cellular Response To Oxidative Stress Cellular Response To Reactive Oxygen Species Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Redox Homeostasis Oxidation-reduction Process Cellular Oxidant Detoxification
Pathways
Drugs			Auranofin Diminazene Benzoic Acid
Diseases
GWAS			Alopecia areata ( 20596022 25608926) Crohn's disease ( 28067908 21102463) Multiple sclerosis ( 31604244 24076602) Psoriasis ( 23143594) Psoriasis vulgaris ( 26626624) Sarcoidosis ( 22837380) Vitiligo ( 27723757)
Interacting Genes		29 interacting genes: AGR2 ANXA7 ARL15 BTBD2 CDKN2B CDKN2C DLEU1 DNM2 EIF2S2 FXYD6 KDM1A LAMTOR1 NACA NIPSNAP3A PAFAH1B3 PCDHA4 PIN1 PNP PRDX5 PSMD11 RGL2 RNF10 SAT1 SDHAF2 SERPINB9 SMN1 TAC3 TK1 TSC22D1	4 interacting genes: APP CCDC90B CLK1 PEX5
Entrez ID		60492	25824
HPRD ID		14378	05958
Ensembl ID		ENSG00000137500	ENSG00000126432
Uniprot IDs		Q9GZT6	P30044
PDB IDs		6H9M	1H4O 1HD2 1OC3 1URM 2VL2 2VL3 2VL9 3MNG 4K7I 4K7N 4K7O 4MMM
Enriched GO Terms of Interacting Partners?
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