BRD2 and HOXC6

		BRD2	HOXC6
Description		bromodomain containing 2	homeobox C6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Nuclear Speck	Nuclear Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	Chromatin Binding Protein Binding Lysine-acetylated Histone Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Activity
	Biological Process	Neural Tube Closure Nucleosome Assembly Regulation Of Transcription By RNA Polymerase II Spermatogenesis Viral Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Anterior/posterior Pattern Specification Embryonic Skeletal System Development Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		RUNX3 regulates p14-ARF
Drugs
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 28008999) Feeling nervous ( 29500382) Inflammatory bowel disease ( 28008999) Ulcerative colitis ( 28008999)	Hippocampal volume ( 25625606) Lumbar spine bone mineral density ( 22504420) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Waist circumference ( 28552196) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28552196 28448500) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		17 interacting genes: CDC42EP4 CLCN2 DDR1 E2F1 E2F2 ECEL1 H2BC21 H2BU1 H4-16 HLA-DQA1 HOXC6 PHF1 PRNP PSMB9 RAC2 SPOP TBP	10 interacting genes: APC APP BCAR3 BRD2 CHEK2 FGFR2 HMGB1 IGF1R PTPRJ TGFB1
Entrez ID		6046	3223
HPRD ID		03326	00858
Ensembl ID		ENSG00000204256	ENSG00000197757
Uniprot IDs		A0A024RCR5 A0A1U9X7A8 P25440 X5CF57	P09630
PDB IDs		1X0J 2DVQ 2DVR 2DVS 2DVV 2E3K 2G4A 2YDW 2YEK 3AQA 3ONI 4A9E 4A9F 4A9H 4A9I 4A9J 4A9M 4A9N 4A9O 4AKN 4ALG 4ALH 4J1P 4MR5 4MR6 4QEU 4QEV 4QEW 4UYF 4UYG 4UYH 5BT5 5DFB 5DFC 5DFD 5DW1 5EK9 5HEL 5HEM 5HEN 5HFQ 5IBN 5IG6 5N2L 5O38 5O39 5O3A 5O3B 5O3C 5O3D 5O3E 5O3F 5O3G 5O3H 5O3I 5U5S 5U6V 5UEW 5XHE 5XHK 6CUI 6DB0 6DBC 6DDI 6DDJ 6E6J 6FFE 6FFF 6FFG 6I80 6I81 6K04 6K05 6MO7 6MO8 6MO9 6MOA
Enriched GO Terms of Interacting Partners?
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