RIT1 and RALGDS

Number of citations of the paper that reports this interaction (PubMedID 10545207)
24

		RIT1	RALGDS
Description		Ras like without CAAX 1	ral guanine nucleotide dissociation stimulator
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GO Annotations	Cellular Component	Plasma Membrane	Nucleus Cytosol Brush Border
	Molecular Function	GTPase Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding GTPase Regulator Activity
	Biological Process	Signal Transduction Ras Protein Signal Transduction	Ras Protein Signal Transduction Regulation Of Catalytic Activity
Pathways		Signalling to p38 via RIT and RIN	p38MAPK events p38MAPK events
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Conduct disorder (maternal expressed emotions interaction) ( 18846501) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233)	Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		15 interacting genes: AFDN AP2A1 CUL3 IFRD1 KLHL12 LRIF1 LRRK2 PTN RALGDS RGL1 RLF SMAD2 SMAD3 SMURF1 SRPK2	23 interacting genes: AFDN ARRB1 ARRB2 CD68 CNKSR1 HRAS KRAS LRPAP1 MAPK3 MRAS NF2 PDPK1 RAP1A RAP1B RAP1GAP RAP2A RAP2B RAPGEF2 RIN1 RIT1 RIT2 RRAS RRAS2
Entrez ID		6016	5900
HPRD ID		10195	03371
Ensembl ID		ENSG00000143622	ENSG00000160271
Uniprot IDs		Q92963	Q12967 Q8N4Y1
PDB IDs		4KLZ	1RAX 2B3A 2RGF 3KH0
Enriched GO Terms of Interacting Partners?
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