RFXAP and RFX5

Number of citations of the paper that reports this interaction (PubMedID 26496610)
285

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)
HPRD (in vivo, two hybrid)

		RFXAP	RFX5
Description		regulatory factor X associated protein	regulatory factor X5
Image
GO Annotations	Cellular Component	Nucleus Nuclear Speck	Nuclear Chromatin Nucleus
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Bare lymphocyte syndrome (BLS) type2 Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency	Bare lymphocyte syndrome (BLS) type2 Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS		Metabolite levels ( 23823483) Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407)	Body mass index ( 26426971)
Interacting Genes		4 interacting genes: EPS8 RFX5 RFXANK SMARCA4	5 interacting genes: APP CIITA HDAC2 RFXANK RFXAP
Entrez ID		5994	5993
HPRD ID		03515	03517
Ensembl ID		ENSG00000133111	ENSG00000143390
Uniprot IDs		O00287	P48382
PDB IDs		2KW3	2KW3 3V30
Enriched GO Terms of Interacting Partners?
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