RFX4 and RFX3

Number of citations of the paper that reports this interaction (PubMedID 11682486)
18

Data Source:
HPRD (in vitro, in vivo)

		RFX4	RFX3
Description		regulatory factor X4	regulatory factor X3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nuclear Chromatin Extracellular Region Nucleus Transcription Factor Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Telencephalon Development Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Positive Regulation Of Transcription By RNA Polymerase II Cilium Assembly Regulation Of Protein Processing	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Endocrine Pancreas Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cell Maturation Regulation Of Insulin Secretion Cilium Assembly Cilium-dependent Cell Motility Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Type B Pancreatic Cell Maturation Positive Regulation Of Type B Pancreatic Cell Development
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Cognitive test performance ( 17903297) Heart rate ( 23583979) Morning person ( 30696823) Night sleep phenotypes ( 27126917) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Triglyceride levels ( 28334899)	Bisphosphonate-associated atypical femoral fracture ( 31006051) Body mass index ( 28552196) Gout ( 25967671) Insomnia ( 29520036) Major depressive disorder ( 27479909) Monobrow thickness ( 26926045) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure in sickle cell anemia ( 24058526) Weight ( 28552196)
Interacting Genes		3 interacting genes: ESR1 RFX2 RFX3	12 interacting genes: BIN1 CREB1 EWSR1 FHL2 FHL3 IRF6 PKNOX1 RFX1 RFX4 RFX6 TRAF2 TRIP6
Entrez ID		5992	5991
HPRD ID		04905	03215
Ensembl ID		ENSG00000111783	ENSG00000080298
Uniprot IDs		Q33E94	P48380
PDB IDs
Enriched GO Terms of Interacting Partners?
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