RAB27B and SYTL1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		RAB27B	SYTL1
Description		RAB27B, member RAS oncogene family	synaptotagmin like 1
Image			No pdb structure
GO Annotations	Cellular Component	Cell Late Endosome Golgi Apparatus Golgi Stack Plasma Membrane Endomembrane System Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane Axon Cytoplasm	Plasma Membrane Extrinsic Component Of Plasma Membrane Microvillus Membrane Melanosome Extracellular Exosome Exocytic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	Protein Binding Rab GTPase Binding Neurexin Family Protein Binding
	Biological Process	Platelet Degranulation Intracellular Protein Transport Melanosome Transport Rab Protein Signal Transduction Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport	Intracellular Protein Transport Exocytosis
Pathways		Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	TBC/RABGAPs
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		8 interacting genes: DHPS MLPH RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D	7 interacting genes: AKT1 NCF1 NCF2 NRXN1 RAB27A RAB27B RAB8A
Entrez ID		5874	84958
HPRD ID		04846	12156
Ensembl ID		ENSG00000041353	ENSG00000142765
Uniprot IDs		O00194	Q8IYJ3
PDB IDs		2F7S
Enriched GO Terms of Interacting Partners?
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