RAB1A and FSCN1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAB1A	FSCN1
Description		RAB1A, member RAS oncogene family	fascin actin-bundling protein 1
Image
GO Annotations	Cellular Component	Golgi Membrane Cell Early Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Membrane Melanosome Extracellular Exosome	Stress Fiber Ruffle Podosome Cytoplasm Cytosol Cytoskeleton Microvillus Cell-cell Junction Cell Cortex Actin Cytoskeleton Lamellipodium Filopodium Growth Cone Cell Projection Membrane Microspike Extracellular Exosome Invadopodium
	Molecular Function	GTPase Activity Protein Binding GTP Binding Cadherin Binding	RNA Binding Actin Binding Protein Binding Drug Binding Protein Binding, Bridging Cadherin Binding Actin Filament Binding
	Biological Process	Autophagosome Assembly Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Endocytosis Autophagy Golgi Organization Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Rab Protein Signal Transduction Substrate Adhesion-dependent Cell Spreading Defense Response To Bacterium Post-translational Protein Modification Vesicle Transport Along Microtubule COPII Vesicle Coating Cilium Assembly Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity	Cell-cell Junction Assembly Establishment Or Maintenance Of Cell Polarity Positive Regulation Of Lamellipodium Assembly Cell Migration Cytokine-mediated Signaling Pathway Microspike Assembly Actin Cytoskeleton Organization Parallel Actin Filament Bundle Assembly Regulation Of Microvillus Assembly Regulation Of Actin Cytoskeleton Organization Establishment Of Apical/basal Cell Polarity Cell Motility Actin Filament Bundle Assembly Positive Regulation Of Filopodium Assembly Positive Regulation Of Podosome Assembly Positive Regulation Of Extracellular Matrix Disassembly
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS
Interacting Genes		31 interacting genes: ADCK1 CAPNS1 CDKN1A CHML CREB1 CSNK1D EBP FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 OCRL PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RABIF RFK RUSC2 SLC16A8 SNRNP27 SNRPG SYT5 TBC1D17 USO1 ZNF593	11 interacting genes: ACTA1 ACTC1 CTNNB1 DNAJB9 MAPK8IP2 NGFR PRKCA PRKCD RAB1A SMURF1 YWHAQ
Entrez ID		5861	6624
HPRD ID		01538	04068
Ensembl ID		ENSG00000138069	ENSG00000075618
Uniprot IDs		B7Z8M7 P62820 Q5U0I6	A0A384MEG1 B3KTA3 Q16658
PDB IDs		2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS	1DFC 3LLP 3P53 4GOV 4GOY 4GP0 4GP3 6B0T 6I0Z 6I10 6I11 6I12 6I13 6I14 6I15 6I16 6I17 6I18
Enriched GO Terms of Interacting Partners?
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