BBS4 and KRT18

Number of citations of the paper that reports this interaction (PubMedID 18000879)
7

Data Source:
BioGRID (two hybrid)

		BBS4	KRT18
Description		Bardet-Biedl syndrome 4	keratin 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Photoreceptor Outer Segment Photoreceptor Inner Segment Cell Nucleus Centrosome Centriole Cytosol Cilium Motile Cilium Photoreceptor Connecting Cilium Centriolar Satellite BBSome Ciliary Transition Zone Ciliary Basal Body Ciliary Membrane Non-motile Cilium	Nucleolus Cytoplasm Microtubule Organizing Center Cytosol Intermediate Filament Adherens Junction Centriolar Satellite Keratin Filament Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Microtubule Motor Activity Protein Binding Dynactin Binding Alpha-tubulin Binding Beta-tubulin Binding	RNA Binding Structural Molecule Activity Protein Binding Scaffold Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cytokinesis Neuron Migration Neural Tube Closure Retina Homeostasis Heart Looping Negative Regulation Of Systemic Arterial Blood Pressure Centrosome Cycle Spermatid Development Visual Perception Sensory Perception Of Smell Negative Regulation Of Gene Expression Protein Transport Dendrite Development Regulation Of Lipid Metabolic Process Ventricular System Development Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Negative Regulation Of Actin Filament Polymerization Melanosome Transport Regulation Of Cytokinesis Protein Localization To Organelle Negative Regulation Of GTPase Activity Microtubule Anchoring At Centrosome Social Behavior Photoreceptor Cell Outer Segment Organization Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Positive Regulation Of Multicellular Organism Growth Fat Cell Differentiation Photoreceptor Cell Maintenance Positive Regulation Of Cilium Assembly Retinal Rod Cell Development Intracellular Transport Brain Morphogenesis Sensory Processing Maintenance Of Protein Location In Nucleus Regulation Of Stress Fiber Assembly Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Face Development Fat Pad Development Protein Localization To Cilium Protein Localization To Centrosome Regulation Of Non-motile Cilium Assembly Protein Localization To Photoreceptor Outer Segment Non-motile Cilium Assembly	Cell Cycle Anatomical Structure Morphogenesis Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Negative Regulation Of Apoptotic Process Intermediate Filament Cytoskeleton Organization Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process Cell-cell Adhesion
Pathways		BBSome-mediated cargo-targeting to cilium	Keratinization Formation of the cornified envelope
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS		Body mass index ( 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Theory of mind score in adolescence (Emotional Triangles Task) ( 29472613) Triglycerides ( 30275531) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Cleft lip with or without cleft palate ( 28054174) Diffusing capacity of carbon monoxide ( 30694715) Nonsyndromic cleft lip with cleft palate ( 28232668)
Interacting Genes		15 interacting genes: ACTB BHMT CALCA DCTN1 EEF1A1 EIF3A EPAS1 EXOC7 FHOD1 HSCB KRT18 MYOG PAX2 PCM1 REL	78 interacting genes: BBS1 BBS2 BBS4 BBS7 CAMK2A CASP3 CASP6 CASP7 CASP8 CBL CCDC146 CCDC85B CCNI CDC5L CDK1 COL17A1 DEDD DNAJB6 EGFR EP300 ESR1 EXOC8 FRAT1 GIT2 GOLGA2 GRN HAUS1 HGS HRAS HSPA1A HSPA4 HSPA5 HSPB1 IKBKG KPNA2 KRT15 KRT5 KRT72 KRT8 LDOC1 MAPK14 NEFL NME7 ORC5 PDE4DIP PIAS4 PKD1 PKP2 PKP3 PNN POT1 PRKCA PRKCE PSTPIP2 RAF1 RHPN2 RPS6KA3 SERPINE1 SHC1 SMARCD1 SVIL SYCE1 TCHP TNFRSF1B TRADD TUBG1 TUBGCP4 TXN2 TXNDC11 UPF2 USH2A WBP2 YTHDC1 YWHAB YWHAE YWHAG YWHAH YWHAZ
Entrez ID		585	3875
HPRD ID		08982	01020
Ensembl ID		ENSG00000140463	ENSG00000111057
Uniprot IDs		A0A0S2Z3A9 Q96RK4	A0A024RAY2 P05783
PDB IDs
Enriched GO Terms of Interacting Partners?
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